Semantic priming refers to the phenomenon that participants typically respond faster to targets following semantically related primes as compared to semantically unrelated primes. In contrast, Wentura and Frings (2005) found a negatively signed priming effect (i.e., faster responses to semantically unrelated as compared to semantically related targets) when they used (a) a special masking technique for the primes and (b) categorically related prime-target-pairs (e.g., fruit-apple). The negatively signed priming effect was most pronounced for participants with random prime discrimination performance, whereas participants with high prime discrimination performance showed a positive effect. In the present study we analyzed the after-effects of masked category primes in audition. A comparable pattern of results as in the visual modality emerged: The poorer the individual prime discrimination, the more negative is the semantic priming effect. This result is interpreted as evidence for a common mechanism causing the semantic priming effect in vision as well as in audition instead of a perceptual mechanism only working in the visual domain.