Phosphorylation of Thr522 activates SIRT1 and is required for DYRK-mediated cell survival in response to DNA damage

被引：0
|
作者：
Li, Xiaoling [1 ]
Guo, Xiumei [1 ]
Williams, Jason [2 ]
Bienstock, Rachelle [3 ]
机构：
[1] NIEHS, Lab Signal Transduct, NIH, Res Triangle Pk, NC 27709 USA
[2] NIEHS, Lab Struct Biol, NIH, Res Triangle Pk, NC 27709 USA
[3] NIEHS, Sci Comp Lab, NIH, Res Triangle Pk, NC 27709 USA
来源：
FASEB JOURNAL | 2010年 / 24卷
关键词：
D O I：
暂无
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
引用
收藏
页数：1
相关论文
共 50 条
  • [1] DYRK1A and DYRK3 Promote Cell Survival through Phosphorylation and Activation of SIRT1
    Guo, Xiumei
    Williams, Jason G.
    Schug, Thaddeus T.
    Li, Xiaoling
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2010, 285 (17) : 13223 - 13232
  • [2] Active regulator of SIRT1 is required for cancer cell survival but not for SIRT1 activity
    Knight, John R. P.
    Allison, Simon J.
    Milner, Jo
    OPEN BIOLOGY, 2013, 3 (11)
  • [3] Sirt1 Promotes DNA Damage Repair and Cellular Survival
    Song, Seung-Hyun
    Lee, Mi-Ok
    Lee, Ji-Seon
    Oh, Je-Sok
    Cho, Sung-Uk
    Cha, Hyuk-Jin
    BIOMOLECULES & THERAPEUTICS, 2011, 19 (03) : 282 - 287
  • [4] DBC1 phosphorylation by ATM/ATR inhibits SIRT1 deacetylase in response to DNA damage
    Zannini, Laura
    Buscemi, Giacomo
    Kim, Ja-Eun
    Fontanella, Enrico
    Delia, Domenico
    JOURNAL OF MOLECULAR CELL BIOLOGY, 2012, 4 (05) : 294 - 303
  • [5] Control of AIF-mediated cell death by the functional interplay of SIRT1 and PARP-1 in response to DNA damage
    Kolthur-Seetharam, Ullas
    Dantzer, Francoise
    McBurney, Michael W.
    de Murcia, Gilbert
    Sassone-Corsi, Paolo
    CELL CYCLE, 2006, 5 (08) : 873 - 877
  • [6] The Role of SIRT1 on DNA Damage Response and Epigenetic Alterations in Cancer
    Alves-Fernandes, Debora Kristina
    Jasiulionis, Miriam Galvonas
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2019, 20 (13):
  • [7] Ubiquitinated Sirtuin 1 (SIRT1) Function Is Modulated during DNA Damage-induced Cell Death and Survival
    Peng, Lirong
    Yuan, Zhigang
    Li, Yixuan
    Ling, Hongbo
    Izumi, Victoria
    Fang, Bin
    Fukasawa, Kenji
    Koomen, John
    Chen, Jiandong
    Seto, Edward
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2015, 290 (14) : 8904 - 8912
  • [8] Impaired DNA damage response, genome instability, and tumorigenesis in SIRT1 mutant mice
    Wang, Rui-Hong
    Sengupta, Kundan
    Li, Cuiling
    Kim, Hyun-Seok
    Cao, Liu
    Xiao, Cuiying
    Kim, Sangsoo
    Xu, Xiaoling
    Zheng, Yin
    Chilton, Beverly
    Jia, Rong
    Zheng, Zhi-Ming
    Appella, Ettore
    Wang, Xin Wei
    Ried, Thomas
    Deng, Chu-Xia
    CANCER CELL, 2008, 14 (04) : 312 - 323
  • [9] A functional link between SIRT1 deacetylase and NBS1 in DNA damage response
    Yuan, Zhigang
    Seto, Edward
    CELL CYCLE, 2007, 6 (23) : 2869 - 2871
  • [10] Post-translational Modification in Control of SIRT1 Stability during DNA Damage Response
    Ouyang, Chenxi
    Lu, Guang
    He, Weifeng
    Bay, Boon-Huat
    Shen, Han-Ming
    INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES, 2022, 18 (07): : 2655 - 2669
12345