Clinical practice guidelines: Concepts, limitations and challenges

Clinical practice guidelines are the most important documents for the incorporation of scientific evidence in health decision making through the formulation of recommendations. There is a variable terminology used to refer to the documents that guide health professionals in decision making. When clinical practice guidelines arc of high quality, they appraise contextual aspects such as the use of resources, applicability, and patients' values and preferences. Even so, they are not recipe books, since they may have limitations. In this review, we propose to clarify the different denominations across the various types of documents available to guide the health professional when making clinical decisions. We discuss the main characteristics of clinical practice guidelines, quality assessment, challenges, and limitations.