Free radical oxidation and antioxidant activity in blood plasma and myocardium during long-term dipyridamole treatment

被引：0
|
作者：
Ivasenko, IN [1 ]
Shlyakhto, EV [1 ]
机构：
[1] IP Pavlov State Med Univ, Inst Cardiovasc Dis, Hematol Lab, St Petersburg, Russia
来源：
BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE | 2001年 / 131卷 / 06期
关键词：
myocardium; plasma; platelets; free radical oxidation; antioxidant activity;
D O I：
10.1023/A:1012342300406
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
Activation of free radical oxidation and inhibition of antioxidant activity in mouse myocardium. after long-term dipyridamole treatment were demonstrated using chemi luminescent techniques. At the same time, dipyridamole 10-fold inhibited free radical oxidation and slightly increased antioxidant activity in the plasma. Dipyridamole-induced platelet disaggregation was accompanied by an increase in platelet count.
引用
收藏
页码：538 / 540
页数：3
相关论文
共 50 条
  • [41] Plasma antioxidant activity and chromosome aberrations in humans exposed to long-term low-dose γ-irradiation
    Marusin, AV
    Popova, NA
    Salyukov, VB
    Stepanov, VA
    Nazarenko, SA
    BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE, 2005, 139 (06) : 703 - 705
  • [42] ACTIVITY PARAMETERS OF CROHNS-DISEASE DURING LONG-TERM TREATMENT WITH METRONIDAZOLE
    GUGLER, R
    JENSEN, JC
    SCHULTE, H
    VOGEL, R
    ZEITSCHRIFT FUR GASTROENTEROLOGIE, 1989, 27 (11): : 676 - 682
  • [43] Plasma Antioxidant Activity and Chromosome Aberrations in Humans Exposed to Long-Term Low-Dose γ-Irradiation
    A. V. Marusin
    N. A. Popova
    V. B. Salyukov
    V. A. Stepanov
    S. A. Nazarenko
    Bulletin of Experimental Biology and Medicine, 2005, 139 : 703 - 705
  • [44] RENIN-ACTIVITY IN RAT PLASMA DURING A LONG-TERM APPLICATION OF LYSINE VASOPRESSIN
    SZADOWSKA, A
    SZMIGIELSKA, H
    POLISH JOURNAL OF PHARMACOLOGY AND PHARMACY, 1973, 25 (05): : 500 - 501
  • [45] RHEOLOGIC PROPERTIES OF BLOOD DURING LONG-TERM AND SHORT-TERM ADAPTATION TO MUSCULAR-ACTIVITY
    LEVIN, VN
    MURAVEV, AV
    BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE, 1985, 99 (02) : 162 - 164
  • [46] LEUKOCYTOSIS DURING LONG-TERM LITHIUM TREATMENT
    YASSA, R
    NEW YORK STATE JOURNAL OF MEDICINE, 1981, 81 (10) : 1479 - 1480
  • [47] TOLERANCE OF TETRABENAZINE DURING LONG-TERM TREATMENT
    MIKKELSEN, BO
    ACTA NEUROLOGICA SCANDINAVICA, 1983, 68 (01): : 57 - 60
  • [48] POLYNEURITIS DURING LONG-TERM TREATMENT BY METRONIDAZOLE
    SAID, G
    GOASGUEN, J
    LAVERDANT, C
    REVUE NEUROLOGIQUE, 1978, 134 (02) : 153 - 153
  • [49] Long-term melatonin administration enhances the antioxidant potential of human plasma maintained after discontinuation of the treatment
    Piechota, Aleksandra
    Lipinska, Stanislawa
    Szemraj, Janusz
    Goraca, Anna
    GENERAL PHYSIOLOGY AND BIOPHYSICS, 2010, 29 (02) : 144 - 150
  • [50] LONG-TERM SURVIVAL AFTER RADICAL TREATMENT FOR CANCER OF THE ESOPHAGUS
    OROURKE, IC
    JOHNSON, DC
    TIVER, KW
    BULL, CA
    LANGLANDS, AO
    FEIGEN, M
    GEBSKI, V
    MCNEIL, R
    MEDICAL JOURNAL OF AUSTRALIA, 1991, 154 (03) : 219 - 220
12345