Free radical oxidation and antioxidant activity in blood plasma and myocardium during long-term dipyridamole treatment

被引：0
|
作者：
Ivasenko, IN [1 ]
Shlyakhto, EV [1 ]
机构：
[1] IP Pavlov State Med Univ, Inst Cardiovasc Dis, Hematol Lab, St Petersburg, Russia
来源：
BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE | 2001年 / 131卷 / 06期
关键词：
myocardium; plasma; platelets; free radical oxidation; antioxidant activity;
D O I：
10.1023/A:1012342300406
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
Activation of free radical oxidation and inhibition of antioxidant activity in mouse myocardium. after long-term dipyridamole treatment were demonstrated using chemi luminescent techniques. At the same time, dipyridamole 10-fold inhibited free radical oxidation and slightly increased antioxidant activity in the plasma. Dipyridamole-induced platelet disaggregation was accompanied by an increase in platelet count.
引用
收藏
页码：538 / 540
页数：3
相关论文
共 50 条
  • [1] Free Radical Oxidation and Antioxidant Activity in Blood Plasma and Myocardium during Long-Term Dipyridamole Treatment
    I. N. Ivasenko
    E. V. Shlyakhto
    Bulletin of Experimental Biology and Medicine, 2001, 131 : 538 - 540
  • [2] PLASMA-RENIN ACTIVITY AND BLOOD-PRESSURE DURING LONG-TERM TREATMENT WITH PROPRANOLOL AND DIURETIC
    NIELSEN, I
    STEINESS, E
    HESSE, B
    ACTA MEDICA SCANDINAVICA, 1977, : 97 - 101
  • [3] A complex of antioxidant vitamins effectively inhibits free-radical oxidation of LDL phospholipids in blood plasma and membrane structures of the liver and myocardium
    Konovalova, GG
    Lisina, MO
    Tikhaze, AK
    Lankin, VZ
    BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE, 2003, 135 (02) : 143 - 146
  • [4] A Complex of Antioxidant Vitamins Effectively Inhibits Free-Radical Oxidation of LDL Phospholipids in Blood Plasma and Membrane Structures of the Liver and Myocardium
    G. G. Konovalova
    M. O. Lisina
    A. K. Tikhaze
    V. Z. Lankin
    Bulletin of Experimental Biology and Medicine, 2003, 135 : 143 - 146
  • [5] BEHAVIOR OF PLASMA-RENIN ACTIVITY DURING LONG-TERM TREATMENT WITH PROPRANOLOL
    WITZGALL, H
    KLAUS, D
    BRAUN, B
    EBEL, H
    ZEHNER, J
    KLINISCHE WOCHENSCHRIFT, 1977, 55 (07): : 351 - 353
  • [6] PROLIFERATIVE ACTIVITY OF CAPILLARY WALL CELLS IN SKELETAL-MUSCLE OF RATS DURING LONG-TERM TREATMENT WITH DIPYRIDAMOLE
    TORNLING, G
    UNGE, G
    ADOLFSSON, J
    LJUNGQVIST, A
    CARLSSON, S
    ARZNEIMITTEL-FORSCHUNG/DRUG RESEARCH, 1980, 30-1 (04): : 622 - 623
  • [7] PLASMA CLONIDINE IN RELATION TO BLOOD-PRESSURE, CATECHOLAMINES, AND RENIN-ACTIVITY DURING LONG-TERM TREATMENT OF HYPERTENSION
    MANHEM, P
    PAALZOW, L
    HOKFELT, B
    CLINICAL PHARMACOLOGY & THERAPEUTICS, 1982, 31 (04) : 445 - 451
  • [8] Plasma antioxidant state in patients undergoing long-term opioid treatment
    Daniela, Ogurcakova
    Ladislv, Kocan
    Jana, Simonova
    Igor, Martuliak
    Frantisek, Sabol
    Janka, Vaskova
    MEDICAL SCIENCE, 2022, 26 (124)
  • [9] Free radical oxidation and antioxidant activity in placenta at premature delivery
    Prokopenko, VM
    Arutjunyan, AV
    FREE RADICAL BIOLOGY AND MEDICINE, 1998, 25 : S96 - S96
  • [10] LONG-TERM TREATMENT OF CONGESTIVE CARDIOMYOPATHIES WITH DIPYRIDAMOLE AND NITRATED DERIVATIVES
    GREC, V
    GRBIC, M
    SIGWART, U
    JAEGER, M
    RIVIER, JL
    SCHWEIZERISCHE MEDIZINISCHE WOCHENSCHRIFT, 1982, 112 (45) : 1630 - 1631
12345