A simple method for the quantitative analysis of resin bound thiol groups

被引:55
作者
Badyal, JP
Cameron, AM
Cameron, NR
Coe, DM
Cox, R
Davis, BG
Oates, LJ
Oye, G
Steel, PG
机构
[1] Univ Durham, Dept Chem, Sci Labs, Durham DH1 3LE, England
[2] GlaxoSmithKline, Med Res Ctr, Stevenage SG1 2NY, Herts, England
基金
英国工程与自然科学研究理事会;
关键词
D O I
10.1016/S0040-4039(01)01820-2
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Non-aqueous solutions of Ellman's reagent [5,5'-dithio(2-nitrobenzoic acid), DTNB] can be used to quantify thiols supported on macroporous polystyrene and TentaGel resins. Organic solutions of Ellman's reagent may also be used as a qualitative tests for thiols on a wider range of solid supports. (C) 2001 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:8531 / 8533
页数:3
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