Autophagy revisited

被引:363
作者
Klionsky, Daniel J. [1 ,2 ]
机构
[1] Univ Michigan, Inst Life Sci, Dept Mol Cellular & Dev Biol, Ann Arbor, MI 48109 USA
[2] Univ Michigan, Inst Life Sci, Dept Biol Chem, Ann Arbor, MI 48109 USA
关键词
glucagon; lysosome; organelles; stress; vacuole;
D O I
10.4161/auto.6398
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
The word "autophagy" was invented by Christian de Duve, the discoverer of lysosomes, who also initiated the first experiments that provided clear biochemical proof of the involvement of lysosomes in this process. I recently had an opportunity to speak with de Duve and some of his former coworkers about their reminiscences of these events, and am pleased to share what they had to say with the readers of this journal, many of whom may not be familiar with this historical background to their field of interest.
引用
收藏
页码:740 / 743
页数:4
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