Effect of low levels of serum vitamin B12 and folic acid on cognitive performance in old age:: A population-based study

被引:0
作者
Jelicic, M
Jonker, C
Deeg, DJH
机构
[1] Univ Maastricht, Dept Psychiat & Neuropsychol, NL-6200 MD Maastricht, Netherlands
[2] Vrije Univ Amsterdam, Dept Psychiat, Amsterdam, Netherlands
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中图分类号
B844 [发展心理学(人类心理学)];
学科分类号
040202 ;
摘要
We studied the effect of low levels of vitamin B(12) and folic acid, alone or combined, on cognitive performance in a population-based sample of 698 older adults (mean age = 68.7 years). No evidence was found for a vitamin-related memory deficit, but research participants with low levels of vitamin B12 exhibited reduced information processing speed relative to participants with normal vitamin B12 levels.
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页码:565 / 571
页数:7
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共 25 条
  • [1] [Anonymous], 2004, Neuropsychological Assessment
  • [2] Major and minor depression in later life: A study of prevalence and risk factors
    Beekman, ATF
    Deeg, DJH
    vanTilburg, T
    Smit, JH
    Hooijer, C
    vanTilburg, W
    [J]. JOURNAL OF AFFECTIVE DISORDERS, 1995, 36 (1-2) : 65 - 75
  • [3] BOHNEN N, 1992, NEUROSCI RES COMMUN, V11, P53
  • [4] de Rooij S, 1994, Tijdschr Gerontol Geriatr, V25, P3
  • [5] DEEG DJH, 1993, NIG TREND STUDIES, V7
  • [6] MINI-MENTAL STATE - PRACTICAL METHOD FOR GRADING COGNITIVE STATE OF PATIENTS FOR CLINICIAN
    FOLSTEIN, MF
    FOLSTEIN, SE
    MCHUGH, PR
    [J]. JOURNAL OF PSYCHIATRIC RESEARCH, 1975, 12 (03) : 189 - 198
  • [7] ASSOCIATION BETWEEN NUTRITIONAL-STATUS AND COGNITIVE-FUNCTIONING IN A HEALTHY ELDERLY POPULATION
    GOODWIN, JS
    GOODWIN, JM
    GARRY, PJ
    [J]. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1983, 249 (21): : 2917 - 2921
  • [8] Further evidence on the effects of vitamin B12 and folate levels on episodic memory functioning:: A population-based study of healthy very old adults
    Hassing, L
    Wahlin, Å
    Winblad, B
    Bäckman, L
    [J]. BIOLOGICAL PSYCHIATRY, 1999, 45 (11) : 1472 - 1480
  • [9] HOLLAND CA, 1991, REV CLIN GERONTOLOGY, V1, P81, DOI [DOI 10.1017/S0959259800002598, 10.1017/S0959259800002598]
  • [10] HULTSCH DF, 1993, J GERONTOL, V48, P1