One-Bit Half Adder-Half Subtractor Logical Operation Based on the DNA Strand Displacement

The DNA strand displacement technology has been widely applied in nano machine, molecular logic circuit, nano medical and other fields. Many molecular logic circuits have been constructed in the recent years. In this paper, one-bit half adder-half subtractor is constructed to achieve two kinds of functions which are half adder function and half subtractor function, respectively. Based on the cascaded DNA strand displacement reactions, the digital logic circuit is further translated into its corresponding dual-rail logic circuit and seesaw cascade logic circuit. The correctness of the simulation results are given to prove the feasibility and effectiveness of the designed circuit, which reduces the complexity of operations and may be applied into DNA biological computer and targeted therapy in the future.