Single-Molecule Approaches Embrace Molecular Cohorts

被引：26

作者：

Ha, Taekjip ^{[1
,2
]}

机构：

[1] Univ Illinois, Howard Hughes Med Inst, Ctr Phys Living Cells, Dept Phys, Urbana, IL 61801 USA

[2] Univ Illinois, Howard Hughes Med Inst, Inst Genom Biol, Urbana, IL 61801 USA

来源：

CELL | 2013年 / 154卷 / 04期

基金：

美国国家科学基金会; 美国国家卫生研究院;

关键词：

UVRD HELICASE; STRANDED-DNA; PROTEINS; MECHANISM; PATHWAYS; EXCHANGE; REVEAL;

D O I：

10.1016/j.cell.2013.07.012

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Enormous mechanistic insight has been gained by studying the behavior of single molecules. The same approaches used to study proteins in isolation are now being leveraged to examine the changes in functional behavior that emerge when single molecules have company.

引用

页码：723 / 726

页数：4

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