ent-Labdane Diterpenes from the Stems of Mallotus japonicus

被引：12

作者：

Li, De-Zheng ^{[1
,2
]}

Tang, Chunping ^{[1
,2
,3
]}

Quinn, Ronald J. ^{[3
]}

Feng, Yunjiang ^{[3
]}

Ke, Chang-Qiang ^{[1
,2
]}

Yao, Sheng ^{[1
,2
]}

Ye, Yang ^{[1
,2
]}

机构：

[1] Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China

[2] Chinese Acad Sci, Shanghai Inst Mat Med, SIMM CUHK Joint Res Lab Promoting Globalizat Trad, Shanghai 201203, Peoples R China

[3] Griffith Univ, Eskitis Inst, Brisbane, Qld 4111, Australia

来源：

JOURNAL OF NATURAL PRODUCTS | 2013年 / 76卷 / 09期

关键词：

GALACTOSAMINE-INDUCED HEPATOTOXICITY; MAJOR CONSTITUENT; PHLOROGLUCINOL DERIVATIVES; CYTOTOXIC CONSTITUENTS; MUELL-ARG; CELL-LINE; PERICARPS; BERGENIN; LIPOPOLYSACCHARIDE; ACETYLBERGENIN;

D O I：

10.1021/np400241p

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Eight new ent-labdane diterpenoids, mallonicusins A-H (1-8), were isolated from the stems of Mallotus japonicus. Their structures, including the absolute configurations, were determined by extensive analyses of spectroscopic data and the ECD spectra of the Pr(FOD)(3) complex of substrates in CCl4. The absolute configuration of compound 1 was confirmed by single-crystal X-ray crystallography using Cu K alpha radiation.

引用

页码：1580 / 1585

页数：6

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