Transcription: Surprising role for an elusive small nuclear RNA

被引：17

作者：

Blencowe, BJ ^{[1
]}

机构：

[1] Univ Toronto, Banting & Best Dept Med Res, CH Best Inst, Toronto, ON M5G 1L6, Canada

来源：

CURRENT BIOLOGY | 2002年 / 12卷 / 04期

关键词：

D O I：

10.1016/S0960-9822(02)00711-X

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Since 7SK was discovered as an abundant small nuclear RNA in the mid-70s, its role has remained tantalizingly unsolved. Two recent studies have shown that 7SK acts as a negative regulator of the RNA polymerase II elongation factor P-TEFb, and that this activity is influenced by stress response pathways.

引用

页码：R147 / R149

页数：3

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