Antihypertensive Therapy and its Efficacy in Outpatient Elderly and Very Elderly Subjects

被引:0
作者
Tkacheva, O. N. [1 ]
Ostapenko, V. S. [1 ]
Runikhina, N. K. [1 ]
Kotovskaya, Yu. V. [2 ]
机构
[1] Pirogov Russian Natl Med Univ, Russian Clin Res Ctr Gerontol, Moscow, Russia
[2] PFUR, Moscow, Russia
关键词
arterial hypertension; elderly patients; combination antihypertensive therapy; COMBINATION; PERINDOPRIL/INDAPAMIDE; HYPERTENSION; INDAPAMIDE;
D O I
10.18565/cardio.2016.11.50-54
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Purpose of the study. The study of the characteristics and effectiveness of antihypertensive therapy (AHT) in patients aged 65 years and older. Material and methods. The study included 356 patients, mean age 74,9 +/- 6,1 years, 80.4% women. The prevalence of arterial hypertension (AH) and the current intake of antihypertensive drugs were evaluated by self-reported patient. Results. The prevalence of hypertension was 88.5%. The predominant variant was isolated systolic hypertension. 51.1% of patients have systolic blood pressure as measured at the reception turned >140 mm Hg in 34.7% of patients >150 mm Hg AHT received 91.6% of patients with hypertension in 65.6% of cases it was combined. Of the various combinations of bicomponent most patients took angiotensin converting enzyme inhibitor in combination with a beta-adrenoblocker or a diuretic. Conclusions. The study showed the high prevalence of hypertension and the lack of efficacy in patients AHT elderly seeking outpatient care.
引用
收藏
页码:50 / 54
页数:7
相关论文
共 11 条
  • [1] Treatment of hypertension in patients 80 years of age or older
    Beckett, Nigel S.
    Peters, Ruth
    Fletcher, Astrid E.
    Staessen, Jan A.
    Liu, Lisheng
    Dumitrascu, Dan
    Stoyanovsky, Vassil
    Antikainen, Riitta L.
    Nikitin, Yuri
    Anderson, Craig
    Belhani, Alli
    Forette, Francoise
    Rajkumar, Chakravarthi
    Thijs, Lutgarde
    Banya, Winston
    Bulpitt, Christopher J.
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2008, 358 (18) : 1887 - 1898
  • [2] Chazova I.E., 2010, SYSTEMIC HYPERTENSIO, V7, P5
  • [3] Perindopril/indapamide combination more effective than enalapril in reducing blood pressure and left ventricular mass:: the PICXEL study
    Dahlof, Bjoern
    Gosse, Philippe
    Gueret, Pascal
    Dubourg, Olivier
    de Simone, Giovanni
    Schmieder, Roland
    Karpov, Yuri
    Garcia-Puig, Juan
    Matos, Lajos
    De Leeuw, Peter W.
    Degaute, Jean-Paul
    Magometschnigg, Dieter
    [J]. JOURNAL OF HYPERTENSION, 2005, 23 (11) : 2063 - 2070
  • [4] Glezer MG, 2016, KARDIOLOGIYA, V56, P18, DOI 10.18565/cardio.2016.1.13-24
  • [5] Compliance, Safety, and Effectiveness of Fixed-Dose Combinations of Antihypertensive Agents A Meta-Analysis
    Gupta, Ajay K.
    Arshad, Shazia
    Poulter, Neil R.
    [J]. HYPERTENSION, 2010, 55 (02) : 399 - 407
  • [6] He W., 2012, SHADES GRAY CROSS CO
  • [7] Karpov YA, 2013, KARDIOLOGIYA, V53, P37
  • [8] [Леонова Марина Васильевна Leonova M.V.], 2015, [Системные гипертензии, Sistemnye gipertenzii], V12, P19
  • [9] Effect of low-dose perindopril/indapamide on albuminuria in diabetes preterax in albuminuria regression: PREMIER
    Mogensen, CE
    Viberti, G
    Halimi, S
    Ritz, E
    Ruilope, L
    Jermendy, G
    Widimsky, J
    Sareli, P
    Taton, J
    Rull, J
    Erdogan, G
    De Leeuw, PW
    Ribeiro, A
    Sanchez, R
    Mechmeche, R
    Nolan, J
    Sirotiakova, J
    Hamani, A
    Scheen, A
    Hess, B
    Luger, A
    Thomas, SM
    [J]. HYPERTENSION, 2003, 41 (05) : 1063 - 1071
  • [10] Effects of a fixed combination of perindopril and indapamide on macrovascular and microvascular outcomes in patients with type 2 diabetes mellitus (the ADVANCE trial): a randomised controlled trial
    Patel, A.
    MacMahon, S.
    Chalmers, J.
    Neal, B.
    Woodward, M.
    Billot, L.
    Harrap, S.
    Poulter, N.
    Marre, M.
    Cooper, M.
    Glasziou, P.
    Grobbee, D. E.
    Hamet, P.
    Heller, S.
    Liu, L. S.
    Mancia, G.
    Mogensen, C. E.
    Pan, C. Y.
    Rodgers, A.
    Williams, B.
    [J]. LANCET, 2007, 370 (9590) : 829 - 840