Recurrent central nervous system blastomycosis in an immunocompetent child treated successfully with sequential liposomal amphotericin B and voriconazole

被引:28
作者
Panicker, J [1 ]
Walsh, T
Kamani, N
机构
[1] Childrens Natl Med Ctr, Div Pediat Hematol Oncol, Washington, DC 20010 USA
[2] NCI, Pediat Branch, NIH, Bethesda, MD 20892 USA
[3] Childrens Natl Med Ctr, Div Stem Cell Transplantat Immunol, Washington, DC 20010 USA
关键词
blastomycosis; voriconazole; amphotericin; immunocompetent;
D O I
10.1097/01.inf.0000207475.89745.51
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Central nervous system involvement in infection with Blastomyces dermatitidis is uncommon, except in immunocompromised patients. We report a case of central nervous system blastomycosis occurring 18 months after treatment of pulmonary blastomycosis in an immunocompetent child. Our patient was successfully treated sequentially with liposomal amphotericin B followed by oral voriconazole without need for surgical resection.
引用
收藏
页码:377 / 379
页数:3
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