One-pot multicomponent synthesis of diazepine derivatives using terminal alkynes in the presence of silica-supported superparamagnetic iron oxide nanoparticles

被引：223
作者：
Maleki, Ali [1 ]
机构：
[1] Iran Univ Sci & Technol, Dept Chem, Tehran 1684613114, Iran
来源：
TETRAHEDRON LETTERS | 2013年 / 54卷 / 16期
基金：
美国国家科学基金会;
关键词：
Superparamagnetic; Nanocatalyst; Multicomponent reaction; Fe3O4/SiO2; nanoparticles; Diazepine; 1,5-BENZODIAZEPINE DERIVATIVES; EFFICIENT; BENZODIAZEPINES; SUBSTITUTION; CATALYSTS; ANALOGS;
D O I：
10.1016/j.tetlet.2013.01.123
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A new, efficient, one-pot multicomponent reaction for the synthesis of diazepine derivatives in excellent yields is described. The reactions of various 1,2-diamines, terminal alkynes, and an isocyanide take place in the presence of a catalytic amount of magnetically recoverable silica-supported superparamagnetic Fe3O4 nanoparticles in ethanol (as a green reaction medium) at ambient temperature. (c) 2013 Elsevier Ltd. All rights reserved.
引用
收藏
页码：2055 / 2059
页数：5
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