Microbial pathogenesis: Genomics and beyond

被引：130

作者：

Strauss, EJ

Falkow, S

机构：

[1] Dept. of Microbiology and Immunology, Stanford University, School of Medicine, Stanford

来源：

SCIENCE | 1997年 / 276卷 / 5313期

关键词：

D O I：

10.1126/science.276.5313.707

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The growing number of complete microbial genome sequences provides a powerful tool for studying the biology of microorganisms. In combination with assays for function, genomic-based approaches can facilitate efficient and directed research strategies to elucidate mechanisms of bacterial pathogenicity. As genomic information accrues, the challenge remains to construct a picture of the biology that accurately reflects how individual genes collaborate to create the complex world of microbial specialization.

引用

页码：707 / 712

页数：6

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