The neXtProt knowledgebase on human proteins: 2017 update

被引:125
作者
Gaudet, Pascale [1 ,2 ]
Michel, Pierre-Andre [1 ]
Zahn-Zabal, Monique [1 ]
Britan, Aurore [1 ]
Cusin, Isabelle [1 ]
Domagalski, Marcin [1 ,2 ]
Duek, Paula D. [1 ]
Gateau, Alain [1 ]
Gleizes, Anne [1 ]
Hinard, Valerie [1 ]
de Laval, Valentine Rech [1 ,2 ]
Lin, JinJin [3 ]
Nikitin, Frederic [1 ]
Schaeffer, Mathieu [1 ,2 ]
Teixeira, Daniel [1 ]
Lane, Lydie [1 ,2 ]
Bairoch, Amos [1 ,2 ]
机构
[1] SIB, CALIPHO Grp, CH-1206 Geneva, Switzerland
[2] Univ Geneva, Dept Human Prot Sci, Fac Med, CH-1206 Geneva, Switzerland
[3] Sun Yat Sen Univ, 135 Xingang W Rd, Guangzhou, Guangdong, Peoples R China
基金
瑞士国家科学基金会;
关键词
HUMAN PROTEOME; PLATFORM; ONTOLOGY; INTACT; STATE;
D O I
10.1093/nar/gkw1062
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The neXtProt human protein knowledgebase (https://www.nextprot.org) continues to add new content and tools, with a focus on proteomics and genetic variation data. neXtProt now has proteomics data for over 85% of the human proteins, as well as new tools tailored to the proteomics community. Moreover, the neXtProt release 2016-08-25 includes over 8000 phenotypic observations for over 4000 variations in a number of genes involved in hereditary cancers and channelopathies. These changes are presented in the current neXtProt update. All of the neXtProt data are available via our user interface and FTP site. We also provide an API access and a SPARQL endpoint for more technical applications.
引用
收藏
页码:D177 / D182
页数:6
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