On the synthesis of 3-acetyl-1-aryl-1,4,5,6-tetrahydro-1H-1,2,4-triazepin-7-ones by reaction of nitrilimines with 3-aminopropanoic acid

被引：2
作者：
Abu Thaher, B
Zahra, JA
El-Abadelah, MM
Otto, HH [1 ]
机构：
[1] Univ Greifswald, Dept Pharmaceut & Med Chem, D-17487 Greifswald, Germany
[2] Islam Univ Gaza, Fac Sci, Dept Chem, Gaza, Israel
[3] Univ Jordan, Fac Sci, Dept Chem, Amman, Jordan
来源：
MONATSHEFTE FUR CHEMIE | 2004年 / 135卷 / 04期
关键词：
arylacetonitrilimines; 1,2,4-triazepin-7-ones; cyclization;
D O I：
10.1007/s00706-003-0092-3
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Nitrilimines were prepared from N-arylhydrazono chlorides and reacted with beta-alanine yielding the corresponding amidrazones, which were treated with 1,1'-carbonyldiimidazole in THF affording the hitherto unknown 3-acetyl-1-aryl-1,4,5,6-tetrahydro-1,2,4-triazepin-7-ones.
引用
收藏
页码：435 / 439
页数：5
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