Predictors of urinary tract infection in acute stroke patients A cohort study

被引:13
作者
Li, Ya-ming [1 ]
Xu, Jian-hua [1 ]
Zhao, Yan-xin [2 ]
机构
[1] Shanghai Univ Med & Hlth Sci, Dept Neurol, Jiading Dist Cent Hosp, Shanghai, Peoples R China
[2] Tongji Univ, Dept Neurol, Peoples Hosp 10, Shanghai, Peoples R China
基金
中国国家自然科学基金;
关键词
hemoglobin; infection; interleukin-6; prediction; stroke; urinary tract infection; ACUTE ISCHEMIC-STROKE; ACUTE MYOCARDIAL-INFARCTION; TO-LYMPHOCYTE RATIO; RISK-FACTORS; ANTIBACTERIAL THERAPY; THROMBOLYTIC THERAPY; CIGARETTE-SMOKE; HEMOGLOBIN; ATHEROSCLEROSIS; INTERLEUKIN-6;
D O I
10.1097/MD.0000000000020952
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Patients with stroke have a high risk of infection which may be predicted by age, procalcitonin, interleukin-6, C-reactive protein, National Institute of Health stroke scale (NHSS) score, diabetes, etc. These prediction methods can reduce unfavourable outcome by preventing the occurrence of infection. We aim to identify early predictors for urinary tract infection in patients after stroke. In 186 collected acute stroke patients, we divided them into urinary tract infection group, other infection type groups, and non-infected group. Data were recorded at admission. Independent risk factors and infection prediction model were determined using Logistic regression analyses. Likelihood ratio test was used to detect the prediction effect of the model. Receiver operating characteristic curve and the corresponding area under the curve were used to measure the predictive accuracy of indicators for urinary tract infection. Of the 186 subjects, there were 35 cases of urinary tract infection. Elevated interleukin-6, higher NIHSS, and decreased hemoglobin may be used to predict urinary tract infection. And the predictive model for urinary tract infection (including sex, NIHSS, interleukin-6, and hemoglobin) have the best predictive effect. This study is the first to discover that decreased hemoglobin at admission may predict urinary tract infection. The prediction model shows the best accuracy.
引用
收藏
页数:10
相关论文
共 103 条
[1]   Hypertension and diabetes mellitus as a predictive risk factors for stroke [J].
Alloubani, Aladeen ;
Saleh, Abdulmoneam ;
Abdelhafiz, Ibrahim .
DIABETES & METABOLIC SYNDROME-CLINICAL RESEARCH & REVIEWS, 2018, 12 (04) :577-584
[2]   High-density lipoprotein-cholesterol and risk of stroke and carotid atherosclerosis: A systematic review [J].
Amarenco, Pierre ;
Labreuche, Julien ;
Touboul, Pierre-Jean .
ATHEROSCLEROSIS, 2008, 196 (02) :489-496
[3]   Optimal achieved blood pressure in acute intracerebral hemorrhage INTERACT2 [J].
Arima, Hisatomi ;
Heeley, Emma ;
Delcourt, Candice ;
Hirakawa, Yoichiro ;
Wang, Xia ;
Woodward, Mark ;
Robinson, Thompson ;
Stapf, Christian ;
Parsons, Mark ;
Lavados, Pablo M. ;
Huang, Yining ;
Wang, Jiguang ;
Chalmers, John ;
Anderson, Craig S. .
NEUROLOGY, 2015, 84 (05) :464-471
[4]  
Ashour Wmr, 2016, J Med Life, V9, P163
[5]   Pneumonia and urinary tract infection after acute ischaemic stroke: a tertiary analysis of the GAIN International trial [J].
Aslanyan, S ;
Weir, CJ ;
Diener, HC ;
Kaste, M ;
Lees, KR .
EUROPEAN JOURNAL OF NEUROLOGY, 2004, 11 (01) :49-53
[6]   The "smoker's paradox" in patients with acute coronary syndrome: a systematic review [J].
Aune, Erlend ;
Roislien, Jo ;
Mathisen, Mariann ;
Thelle, Dag S. ;
Otterstad, Jan Erik .
BMC MEDICINE, 2011, 9
[7]   CLASSIFICATION AND NATURAL-HISTORY OF CLINICALLY IDENTIFIABLE SUBTYPES OF CEREBRAL INFARCTION [J].
BAMFORD, J ;
SANDERCOCK, P ;
DENNIS, M ;
BURN, J ;
WARLOW, C .
LANCET, 1991, 337 (8756) :1521-1526
[8]   SIGNIFICANCE OF SMOKING IN PATIENTS RECEIVING THROMBOLYTIC THERAPY FOR ACUTE MYOCARDIAL-INFARCTION - EXPERIENCE GLEANED FROM THE INTERNATIONAL TISSUE PLASMINOGEN-ACTIVATOR STREPTOKINASE MORTALITY TRIAL [J].
BARBASH, GI ;
WHITE, HD ;
MODAN, M ;
DIAZ, R ;
HAMPTON, JR ;
HEIKKILA, J ;
KRISTINSSON, A ;
MOULOPOULOS, S ;
ERNESTO ;
PAOLASSO ;
VANDERWERF, T ;
PEHRSSON, K ;
SANDOE, E ;
SIMES, J ;
WILCOX, RG ;
VERSTRAETE, M ;
VONDERLIPPE, G ;
VANDEWERF, F .
CIRCULATION, 1993, 87 (01) :53-58
[9]   Acute cigarette smoke exposure reduces clot lysis - association between altered fibrin architecture and the response to t-PA [J].
Barua, Rajat S. ;
Sy, Fridolin ;
Srikanth, Sundararajan ;
Huang, Grace ;
Javed, Usman ;
Buhari, Cyrus ;
Margosan, Dennis ;
Aftab, Waqas ;
Ambrose, John A. .
THROMBOSIS RESEARCH, 2010, 126 (05) :426-430
[10]   Volatile anesthetic preconditioning attenuated sepsis induced lung inflammation [J].
Bedirli, Nurdan ;
Demirtas, Canan Yilmaz ;
Akkaya, Taylan ;
Salman, Bulent ;
Alper, Murat ;
Bedirli, Abdulkadir ;
Pasaoglu, Hatice .
JOURNAL OF SURGICAL RESEARCH, 2012, 178 (01) :E17-E23