Stimulation of brown adipose tissue by polyphenols in extra virgin olive oil

被引：10

作者：

Rodriquez, L. Melguizo ^{[1
,2
,3
]}

Illescas-Montes, R. ^{[2
,3
]}

Costela-Ruiz, V. J. ^{[2
,3
]}

Garcia-Martinez, O. ^{[2
,3
]}

机构：

[1] Univ Granada, Fac Hlth Sci Ceuta, Biomed Grp BIO277, Dept Nursing, Ceuta, Spain

[2] Ibs Granada, Inst Invest Biosanitaria, Granada, Spain

[3] Univ Granada, Biomed Grp BIO277, Dept Nursing, Fac Hlth Sci, Granada, Spain

来源：

CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION | 2021年 / 61卷 / 20期

关键词：

brown adipose tissue; extra virgin olive oil; phenolic compounds; obesity; UNCOUPLING PROTEIN-1 CONTENT; PHENOLIC-COMPOUNDS; GALLIC ACID; ENHANCES NORADRENALINE; ADRENALINE SECRETIONS; INSULIN-RESISTANCE; TRANSPORT ACTIVITY; METABOLIC SYNDROME; VANILLIC ACID; FATTY-ACIDS;

D O I：

10.1080/10408398.2020.1799930

中图分类号：

TS2 [食品工业];

学科分类号：

0832 ;

摘要：

Obesity is one of the main public health problems of the 21(st)century resulting from an imbalance between calorie intake and energy expenditure. Currently, the search for new treatments against this pathology has become a priority. One of the therapeutic strategies against obesity could be the activation of brown adipose tissue through different molecules such as the phenolic compounds of extra virgin olive oil (EVOO). The objective of this review was to provide an update of scientific knowledge on the relationship between EVOO phenolic compounds and brown adipose tissue. According to this review, it has been demonstrated that extra virgin olive oil phenolic compounds can have beneficial effects on obesity by activating brown adipose tissue and enhance thermogenesis through different signaling pathways mediated by molecules such as AMP-activated protein kinase (AMPK), peroxisome proliferator-activated receptor gamma coactivator-1 alpha (PGC1 alpha) or sirtuin 1 (Sirt1).

引用

页码：3481 / 3488

页数：8

共 109 条

[1] Association of Objectively Measured Physical Activity With Brown Adipose Tissue Volume and Activity in Young Adults [J].