Extensively Drug-Resistant Tuberculosis: A Case Report and Literature Review

被引：7

作者：

de Araujo-Filho, Joao Alves ^{[1
]}

Vasconcelos-, Arioldo Carvalho, Jr. ^{[1
]}

de Sousa, Eduardo Martins ^{[1
]}

da Silveira, Colombina

Ribeiro, Elisangela ^{[2
]}

Kipnis, Andre ^{[1
]}

Junqueira-Kipnis, Ana Paula ^{[1
]}

机构：

[1] Univ Fed Goias, Inst Trop Pathol & Publ Hlth, BR-74605050 Goiania, Go, Brazil

[2] Assoc Combate Canc, Araujo Jorge Hosp, Goiania, Go, Brazil

来源：

BRAZILIAN JOURNAL OF INFECTIOUS DISEASES | 2008年 / 12卷 / 05期

关键词：

Extensively drug-resistant tuberculosis; XDR-TB; tuberculosis; Mycobacterium tuberculosis;

D O I：

10.1590/S1413-86702008000500019

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Extensively drug-resistant tuberculosis (XDR-TB) is an emerging health problem that threatens tuberculosis (TB) control worldwide, since suitable treatment for this disease has not yet been found. We report a case of secondary pulmonary XDR-TB in a 54-year-old, HIV-negative male from Goiania, Brazil. The patient had long-standing pulmonary tuberculosis (nine years) with extensive bilateral lung damage and had been treated with multiple antituberculosis drugs (self-administered) before XDR-TB diagnosis. The strain of Mycobacterium tuberculosis was resistant to R-rifampicin, H-isoniazid, E-ethambutol, Eto-ethionamide, Ofx-ofloxacin, and Am-amikacin. This patient died with multiple organ failure due to sepsis secondary to bacterial pneumonia.

引用

页码：447 / 452

页数：6

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