Dissociating cognitive and sensory neural plasticity in human superior temporal cortex

被引：101

作者：

Cardin, Velia ^{[1
,2
]}

Orfanidou, Eleni ^{[1
,3
]}

Roennberg, Jerker ^{[2
]}

Capek, Cheryl M. ^{[4
]}

Rudner, Mary ^{[2
]}

Woll, Bencie ^{[1
]}

机构：

[1] UCL, Cognit Perceptual & Brain Sci Dept, Deafness Cognit & Language Res Ctr, London WC1H 0PD, England

[2] Linkoping Univ, Linnaeus Ctr HEAD, Swedish Inst Disabil Res, Dept Behav Sci & Learning, S-58183 Linkoping, Sweden

[3] Univ Crete, Dept Psychol, Iraklion 74100, Greece

[4] Univ Manchester, Sch Psychol Sci, Ctr Clin & Cognit Neurosci, Manchester M13 9PL, Lancs, England

来源：

NATURE COMMUNICATIONS | 2013年 / 4卷

基金：

瑞典研究理事会; 英国经济与社会研究理事会;

关键词：

BRITISH SIGN-LANGUAGE; AUDITORY-CORTEX; BRAIN; DEAF; NEUROBIOLOGY; USERS; BSL;

D O I：

10.1038/ncomms2463

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Disentangling the effects of sensory and cognitive factors on neural reorganization is fundamental for establishing the relationship between plasticity and functional specialization. Auditory deprivation in humans provides a unique insight into this problem, because the origin of the anatomical and functional changes observed in deaf individuals is not only sensory, but also cognitive, owing to the implementation of visual communication strategies such as sign language and speechreading. Here, we describe a functional magnetic resonance imaging study of individuals with different auditory deprivation and sign language experience. We find that sensory and cognitive experience cause plasticity in anatomically and functionally distinguishable substrates. This suggests that after plastic reorganization, cortical regions adapt to process a different type of input signal, but preserve the nature of the computation they perform, both at a sensory and cognitive level.

引用

页数：5

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