Granulocytic sarcoma of the pancreas on 18F-FDG PET/CT A case report

被引：8

作者：

Ishii, Akira ^{[1
]}

Kondo, Tadakazu ^{[1
]}

Oka, Tomomi ^{[1
]}

Nakamoto, Yuji ^{[2
]}

Takaori-Kondo, Akifumi ^{[1
]}

机构：

[1] Kyoto Univ, Grad Sch Med, Dept Hematol & Oncol, Kyoto, Japan

[2] Kyoto Univ, Grad Sch Med, Dept Diagnost Imaging & Nucl Med, Kyoto, Japan

来源：

MEDICINE | 2016年 / 95卷 / 49期

关键词：

F-18-FDG PET/CT; granulocytic sarcoma; pancreas; ACUTE MYELOID-LEUKEMIA; STEM-CELL TRANSPLANTATION; CHEMOTHERAPY;

D O I：

10.1097/MD.0000000000005570

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Rationale: Granulocytic sarcoma (GS) is defined as leukemia infiltration in any organ other than the bone marrow. GS rarely occurs in the pancreas. Here, we present the first report of GS in the pancreas on F-18-fluorodexyglucose positron emission tomography/ computed tomography (F-18-FDG PET/CT). Patient concerns: A 19-year-old male patient with acute myeloid leukemia received a human leukocyte antigen-haploidentical stem cell transplant as a second transplant while in second complete remission. Interventions: After a second stem cell transplant, obstructive pancreatitis accompanied by a mass in the pancreatic head was observed. FDG-PET/CT revealed abnormal activity in the head of the pancreas and the skin in the patient's left breast area. Diagnoses: Pathological examination demonstrated relapsed acute myeloid leukemia in both the lesions. Outcomes: This is the first report showing the F-18-FDG PET/CT findings of GS in the pancreas. Lessons: F-18-FDG PET/CT may help determine the stage of GS.

引用

页数：3

共 19 条

[1] Granulocytic sarcoma of the pancreas successfully treated with intensive chemotherapy and stem cell transplantation [J].

Breccia, M ;

D'Andrea, M ;

Mengarelli, A ;

Morano, SG ;

D'Elia, GM ;

Alimena, G .

EUROPEAN JOURNAL OF HAEMATOLOGY, 2003, 70 (03) :190-192

[2] 18FDG-PET/CT: 21st century approach to leukemic tumors in 124 cases [J].

Cunningham, Isabel ;

Kohno, Brigett .

AMERICAN JOURNAL OF HEMATOLOGY, 2016, 91 (04) :379-384

[3] Isolated Granulocytic Sarcoma of the Breast after Allogeneic Stem Cell Transplantation: A Rare Involvement Also Detected by 18FDG-PET/CT [J].

Gunduz, Eren ;

Akay, Meltem Olga ;

Karagulle, Mustafa ;

Ak, Ilknur Sivrikoz .

TURKISH JOURNAL OF HEMATOLOGY, 2014, 31 (01) :88-91

[4]

Kamada Y, 2011, ISRN HEMATOL, V2011

[5] FLT3-internal tandem duplication in a pediatric patient with t(8;21) acute myeloid leukemia [J].

Kawamura, Machiko ;

Kaku, Hidefumi ;

Ito, Tateki ;

Funata, Nobuaki ;

Taki, Tomohiko ;

Shimada, Akira ;

Hayashi, Yasuhide .

CANCER GENETICS AND CYTOGENETICS, 2010, 203 (02) :292-296

[6]

KING DJ, 1987, CANCER-AM CANCER SOC, V60, P114, DOI 10.1002/1097-0142(19870701)60:1<114::AID-CNCR2820600121>3.0.CO

[7]

2-G

[8] Isolated pancreatic granulocytic sarcoma: A case report and review if the literature [J].

Li, Xin-Ping ;

Liu, Wen-Fang ;

Ji, Shu-Rong ;

Wu, She-Hua ;

Sun, Jian-Jun ;

Fan, Yue-Zu .

WORLD JOURNAL OF GASTROENTEROLOGY, 2011, 17 (04) :540-542

[9] Abdominal granulocytic sarcomas: Demonstration by MRI [J].

Marcos, HB ;

Semelka, RC ;

Woosley, JT .

MAGNETIC RESONANCE IMAGING, 1997, 15 (07) :873-876

[10] Isolated granulocytic sarcoma of the pancreas: A tricky diagnostic for primary pancreatic extramedullary acute myeloid leukemia [J].

Messager, Mathieu ;

Amielh, David ;

Chevallier, Caroline ;

Mariette, Christophe .

WORLD JOURNAL OF SURGICAL ONCOLOGY, 2012, 10

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