Spontaneous clearance of chronic hepatitis C infection in a patient with a 20-year-old HIV-hepatitis C co-infection and chronic active hepatitis

被引:7
作者
Manfredi, R. [1 ]
Dentale, N. [1 ]
Calza, L. [1 ]
机构
[1] Alma Mater Studiorum Univ Bologna, S Orsola Malpighi Hosp, Div Infect Dis, Dept Internal Med Aging & Nephrol Dis, I-40138 Bologna, Italy
关键词
HIV; hepatitis C; HCV-HIV co-infection; spontaneous HCV clearance; antiretroviral therapy; protease inhibitors; HUMAN-IMMUNODEFICIENCY-VIRUS; PROTEASE INHIBITORS; HAART; THERAPY; VIREMIA;
D O I
10.1258/ijsa.2009.009333
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
We report a case of spontaneous clearance of hepatitis C virus (HCV) in a patient co-infected for 20 years with HCV and HIV, and with an chronic active hepatitis C never treated with anti-HCV regimens. We review the literature of eight anecdotal reports describing the spontaneous resolution of chronic HCV infection among HIV-infected patients, and discuss the virological, immunological, pathogenetic and therapeutic implications of this observation.
引用
收藏
页码:E48 / E50
页数:3
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