A novel and facile synthesis of 2-(cyclohexylamino)-6,7-dihydro-3-aryl-1H-indole-4(5H)-ones via a one-pot multi-component reaction

被引：70

作者：

Heravi, Majid M. ^{[1
]}

Baghernejad, Bita ^{[1
]}

Oskooie, Hossein A. ^{[1
]}

Hekmatshoar, Rahim ^{[1
]}

机构：

[1] Alzahra Univ, Sch Sci, Dept Chem, Tehran, Iran

来源：

TETRAHEDRON LETTERS | 2008年 / 49卷 / 42期

关键词：

cyclohexyl isocyanide; 1,3-dicarbonyl compound; multi-component reaction; 1H-indole-4(5H)-ones;

D O I：

10.1016/j.tetlet.2008.08.012

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A simple and efficient synthesis of 2-(cyclohexylamino)-6,7-dihydro-3-aryl-1H-indole-4(5H)-ones was achieved via a one-pot multi-component reaction of cyclohexyl isocyanide, an aldehyde, a 1,3-dicarbonyl compound, and ammonium acetate in the presence of a catalytic amount of KHSO4 in acetonitrile. (C) 2008 Elsevier Ltd. All rights reserved.

引用

页码：6101 / 6103

页数：3

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