Potential applications of optical coherence tomography angiography in glaucoma

被引:16
作者
Dastiridou, Anna [1 ,2 ]
Chopra, Vikas [2 ,3 ]
机构
[1] Univ Thessalia, Dept Ophthalmol, Thessalia, Greece
[2] Univ Calif Los Angeles, David Geffen Sch Med, Doheny Eye Inst, Doheny Image Reading Ctr, Los Angeles, CA 90095 USA
[3] Univ Calif Los Angeles, David Geffen Sch Med, Dept Ophthalmol, Los Angeles, CA 90095 USA
关键词
glaucoma; macula; nerve fiber layer; optical coherence tomography angiography; ocular perfusion; optic disc; optical coherence tomography; retinal microvasculature; OPEN-ANGLE GLAUCOMA; VESSEL DENSITY; PERIPAPILLARY RETINA; OCT ANGIOGRAPHY; MICROVASCULATURE DROPOUT; HEALTHY; PERFUSION; DEFECTS; SUSPECT; EYES;
D O I
10.1097/ICU.0000000000000475
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
Purpose of reviewOptical coherence tomography angiography (OCTA) is a novel, noninvasive imaging modality that allows assessment of the retinal and choroidal vasculature. The scope of this review is to summarize recent studies using OCTA in glaucoma and highlight potential applications of this new technology in the field of glaucoma.Recent findingsOCTA studies have shown that retinal vascular changes may not develop solely as a result of advanced glaucoma damage. OCTA-derived measurements have provided evidence for lower retinal vascular densities at the optic nerve head, peripapillary and macula in preperimetric-glaucoma and early-glaucoma, as well as, in more advanced glaucoma, in comparison to with normal eyes.SummaryOCTA is a novel imaging modality that has already started to expand our knowledge base regarding the role of ocular blood flow in glaucoma. Future studies will better elucidate the role of OCTA-derived measurements in clinical practice, research, and clinical trials in glaucoma.
引用
收藏
页码:226 / 233
页数:8
相关论文
共 38 条
  • [1] Microvascular Density in Glaucomatous Eyes With Hemifield Visual Field Defects: An Optical Coherence Tomography Angiography Study
    Akagi, Tadamichi
    Iida, Yuto
    Nakanishi, Hideo
    Terada, Noriko
    Morooka, Satoshi
    Yamada, Hiroshi
    Hasegawa, Tomoko
    Yokota, Satoshi
    Yoshikawa, Munemitsu
    Yoshimura, Nagahisa
    [J]. AMERICAN JOURNAL OF OPHTHALMOLOGY, 2016, 168 : 237 - 249
  • [2] Akil H, 2017, BR J OPHTHALMOL
  • [3] Retinal vessel density from optical coherence tomography angiography to differentiate early glaucoma, pre-perimetric glaucoma and normal eyes
    Akil, Handan
    Huang, Alex S.
    Francis, Brian A.
    Sadda, Sirinivas R.
    Chopra, Vikas
    [J]. PLOS ONE, 2017, 12 (02):
  • [4] Optic Disc Perfusion in Primary Open Angle and Normal Tension Glaucoma Eyes Using Optical Coherence Tomography-Based Microangiography
    Bojikian, Karine D.
    Chen, Chieh-Li
    Wen, Joanne C.
    Zhang, Qinqin
    Xin, Chen
    Gupta, Divakar
    Mudumbai, Raghu C.
    Johnstone, Murray A.
    Wang, Ruikang K.
    Chen, Philip P.
    [J]. PLOS ONE, 2016, 11 (05):
  • [5] Angiography of the retina and the choroid with phase-resolved OCT using interval-optimized backstitched B-scans
    Braaf, Boy
    Vermeer, Koenraad A.
    Vienola, Kari V.
    de Boer, Johannes F.
    [J]. OPTICS EXPRESS, 2012, 20 (18): : 20516 - 20534
  • [6] Trabeculectomy Can Improve Long-Term Visual Function in Glaucoma
    Caprioli, Joseph
    de Leon, John Mark
    Azarbod, Parham
    Chen, Andrew
    Morales, Esteban
    Nouri-Mahdavi, Kouros
    Coleman, Anne
    Yu, Fei
    Afifi, Abdelmonem
    [J]. OPHTHALMOLOGY, 2016, 123 (01) : 117 - 128
  • [7] Peripapillary Retinal Nerve Fiber Layer Vascular Microcirculation in Glaucoma Using Optical Coherence Tomography-Based Microangiography
    Chen, Chieh-Li
    Zhang, Anqi
    Bojikian, Karine D.
    Wen, Joanne C.
    Zhang, Qinqin
    Xin, Chen
    Mudumbai, Raghu C.
    Johnstone, Murray A.
    Chen, Philip P.
    Wang, Ruikang K.
    [J]. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2016, 57 (09) : OCT475 - OCT485
  • [8] Optical Coherence Tomography Angiography of the Superficial Microvasculature in the Macular and Peripapillary Areas in Glaucomatous and Healthy Eyes
    Chen, Henry Shen-Lih
    Liu, Chun-Hsiu
    Wu, Wei-Chi
    Tseng, Hsiao-Jung
    Lee, Yung-Sung
    [J]. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2017, 58 (09) : 3637 - 3645
  • [9] Quantitative optical coherence tomography angiography of macular vascular structure and foveal avascular zone in glaucoma
    Choi, Jaewan
    Kwon, Junki
    Shin, Joong Won
    Lee, Jiyun
    Lee, Saem
    Kook, Michael S.
    [J]. PLOS ONE, 2017, 12 (09):
  • [10] Ocular blood flow and systemic blood pressure in patients with primary open-angle glaucoma and ocular hypertension
    Fuchsjäger-Mayrl, G
    Wally, B
    Georgopoulos, M
    Rainer, G
    Kircher, K
    Buehl, W
    Amoako-Mensah, T
    Eichler, HG
    Vass, C
    Schmetterer, L
    [J]. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2004, 45 (03) : 834 - 839