N-type calcium channel blockers from a marine bacterium, Cytophaga sp. SANK 71996

被引：17

作者：

Morishita, T

Sato, A

Hisamoto, M

Oda, T

Matsuda, K

Ishii, A

Kodama, K

机构：

[1] SANKYO CO LTD,BIOMED RES LABS,SHINAGAWA KU,TOKYO 140,JAPAN

[2] SANKYO CO LTD,NEUROSCI RES LABS,SHINAGAWA KU,TOKYO 140,JAPAN

[3] SANKYO CO LTD,TSUKUBA RES LABS,TSUKUBA,IBARAKI 305,JAPAN

来源：

JOURNAL OF ANTIBIOTICS | 1997年 / 50卷 / 06期

关键词：

D O I：

10.7164/antibiotics.50.457

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

N-(3-Acyloxyacyl)glycines were isolated as N-type calcium channel blockers from a marine bacterium Cytophaga sp. SANK 71996. The identification and fermentation of the producing strain and structure characterization of N-(3-acyloxyacyl)glycines by spectral analyses and chemical syntheses are described together with their antagonistic activities.

引用

页码：457 / 468

页数：12

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