N-type calcium channel blockers from a marine bacterium, Cytophaga sp. SANK 71996

被引：17
|
作者：
Morishita, T
Sato, A
Hisamoto, M
Oda, T
Matsuda, K
Ishii, A
Kodama, K
机构：
[1] SANKYO CO LTD,BIOMED RES LABS,SHINAGAWA KU,TOKYO 140,JAPAN
[2] SANKYO CO LTD,NEUROSCI RES LABS,SHINAGAWA KU,TOKYO 140,JAPAN
[3] SANKYO CO LTD,TSUKUBA RES LABS,TSUKUBA,IBARAKI 305,JAPAN
来源：
JOURNAL OF ANTIBIOTICS | 1997年 / 50卷 / 06期
关键词：
D O I：
10.7164/antibiotics.50.457
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
N-(3-Acyloxyacyl)glycines were isolated as N-type calcium channel blockers from a marine bacterium Cytophaga sp. SANK 71996. The identification and fermentation of the producing strain and structure characterization of N-(3-acyloxyacyl)glycines by spectral analyses and chemical syntheses are described together with their antagonistic activities.
引用
收藏
页码：457 / 468
页数：12
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