COVID-19 vaccine research and development: ethical issues

被引:55
作者
Wibawa, T. [1 ,2 ]
机构
[1] Univ Gadjah Mada, Fac Med Publ Hlth & Nursing, Dept Microbiol, Yogyakarta, Indonesia
[2] Univ Gadjah Mada, Fac Med Publ Hlth & Nursing, Dr Sardjito Gen Hosp, Med & Hlth Res Eth Comm, Yogyakarta, Indonesia
关键词
COVID-19; vaccine research; ethics; INFECTION;
D O I
10.1111/tmi.13503
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
The achievements of vaccine research and development bring a hope to our societies that we may cope with the COVID-19 pandemic. There are two aspects that should be maintained in balance: the immediate necessity for speed of vaccine research and the inherent need for protection of research subjects, which is the foremost concern of research ethics. This narrative review highlights ethical issues in COVID-19 vaccine research and development that every stakeholder needs to be aware of and to consider.
引用
收藏
页码:14 / 19
页数:6
相关论文
共 40 条
[1]   SARS-CoV-2 Vaccines: Status Report [J].
Amanat, Fatima ;
Krammer, Florian .
IMMUNITY, 2020, 52 (04) :583-589
[2]   Health Providers' Perceptions of Clinical Trials: Lessons from Ghana, Kenya and Burkina Faso [J].
Angwenyi, Vibian ;
Asante, Kwaku-Poku ;
Traore, Abdoulaye ;
Febir, Lawrence Gyabaa ;
Tawiah, Charlotte ;
Kwarteng, Anthony ;
Ouedraogo, Alphonse ;
Sirima, Sodiomon Bienvenue ;
Owusu-Agyei, Seth ;
Imoukhuede, Egeruan Babatunde ;
Webster, Jayne ;
Chandramohan, Daniel ;
Molyneux, Sassy ;
Jones, Caroline .
PLOS ONE, 2015, 10 (05)
[3]  
[Anonymous], 2020, 1DAYSOONER
[4]  
[Anonymous], 2020, THE NEW YORK TIME
[5]   COVID-19: towards understanding of pathogenesis [J].
Cao, Wei ;
Li, Taisheng .
CELL RESEARCH, 2020, 30 (05) :367-369
[6]   Single-dose Live Oral Cholera Vaccine CVD 103-HgR Protects Against Human Experimental Infection With Vibrio cholerae O1 El Tor [J].
Chen, Wilbur H. ;
Cohen, Mitchell B. ;
Kirkpatrick, Beth D. ;
Brady, Rebecca C. ;
Galloway, David ;
Gurwith, Marc ;
Hall, Robert H. ;
Kessler, Robert A. ;
Lock, Michael ;
Haney, Douglas ;
Lyon, Caroline E. ;
Pasetti, Marcela F. ;
Simon, Jakub K. ;
Szabo, Flora ;
Tennant, Sharon ;
Levine, Myron M. .
CLINICAL INFECTIOUS DISEASES, 2016, 62 (11) :1329-1335
[7]   Current global vaccine and drug efforts against COVID-19: Pros and cons of bypassing animal trials [J].
Deb, Bijayeeta ;
Shah, Hemal ;
Goel, Suchi .
JOURNAL OF BIOSCIENCES, 2020, 45 (01)
[8]   Accelerating Development of SARS-CoV-2 Vaccines - The Role for Controlled Human Infection Models [J].
Deming, Meagan E. ;
Michael, Nelson L. ;
Robb, Merlin ;
Cohen, Myron S. ;
Neuzil, Kathleen M. .
NEW ENGLAND JOURNAL OF MEDICINE, 2020, 383 (10)
[9]  
Dowling W, 2020, COVID 19 ANIMAL MODE
[10]  
Enayatkhani M, 2021, J BIOMOL STRUCT DYN, V39, P2857, DOI [10.1080/07391102.2020.1857843, 10.1080/07391102.2020.1756411]