Identifying the Human Cytochrome P450 Isoforms Involved in the Enantioselective Metabolism of 2,2′,3,4′,6-Pentachlorobiphenyl (PCB 91)

被引:0
|
作者
Uwiman, E. [1 ]
Lehmler, H. J. [1 ]
机构
[1] Univ Iowa, Interdisciplinary Grad Program Human Toxicol, Iowa City, IA USA
关键词
D O I
暂无
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
P144
引用
收藏
页码:73 / 73
页数:1
相关论文
共 50 条
  • [21] The cytochrome P450 system .2. 3A3,4
    Stahl, SM
    PSYCHIATRIC ANNALS, 1997, 27 (07) : 469 - 470
  • [22] Characterization of human cytochrome P450 isoforms involved in the metabolism of 7-epi-paclitaxel
    Zhang, Y. -Y.
    Liu, Y.
    Zhang, J. -W.
    Ge, G. -B.
    Wang, L. -M.
    Sun, J.
    Yang, L.
    XENOBIOTICA, 2009, 39 (04) : 283 - 292
  • [23] 2,2′,3,5′,6-Pentachlorobiphenyl (PCB 95) Is Atropselectively Metabolized to para-Hydroxylated Metabolites by Human Liver Microsomes
    Uwimana, Eric
    Li, Xueshu
    Lehmler, Hans-Joachim
    CHEMICAL RESEARCH IN TOXICOLOGY, 2016, 29 (12) : 2108 - 2110
  • [24] Human reductive halothane metabolism in vitro is catalyzed by cytochrome P450 2A6 and 3A4
    Spracklin, DK
    Thummel, KE
    Kharasch, ED
    DRUG METABOLISM AND DISPOSITION, 1996, 24 (09) : 976 - 983
  • [25] Embryonic Exposure to 2,2′,3,5′,6-pentachlorobiphenyl (PCB-95) Causes Developmental Malformations in Zebrafish
    Ranasinghe, Prabha
    Thorn, Robert J.
    Seto, Renee
    Creton, Robbert
    Bridges, William C.
    Chapman, Susan C.
    Lee, Cindy M.
    ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY, 2020, 39 (01) : 162 - 170
  • [26] Predicting Drug Metabolism by Cytochrome P450 2C9: Comparison with the 2D6 and 3A4 Isoforms
    Rydberg, Patrik
    Olsen, Lars
    CHEMMEDCHEM, 2012, 7 (07) : 1202 - 1209
  • [27] Stereoselective induction by 2,2′,3,4′,6-pentachlorobiphenyl in adult zebrafish (Danio rerio): Implication of chirality in oxidative stress and bioaccumulation
    Chai, Tingting
    Cui, Feng
    Mu, Xiyan
    Yang, Yang
    Qi, Suzhen
    Zhu, Lizhen
    Wang, Chengju
    Qiu, Jing
    ENVIRONMENTAL POLLUTION, 2016, 215 : 66 - 76
  • [28] 2,2′,3,5′,6-Pentachlorobiphenyl (PCB 95) and Its Hydroxylated Metabolites Are Enantiomerically Enriched in Female Mice
    Kania-Korwel, Izabela
    Barnhart, Christopher D.
    Stamou, Marianna
    Truong, Kim M.
    El-Komy, Mohammed H. M. E.
    Lein, Pamela J.
    Veng-Pedersen, Peter
    Lehmler, Hans-Joachim
    ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2012, 46 (20) : 11393 - 11401
  • [29] 2,2′,3,3′,6,6′-hexachlorobiphenyl (PCB 136) atropisomers interact enantioselectively with hepatic microsomal cytochrome P450 enzymes
    Kania-Korwel, Izabela
    Hrycay, Eugene G.
    Bandiera, Stelvio M.
    Lehmler, Hans-Joachim
    CHEMICAL RESEARCH IN TOXICOLOGY, 2008, 21 (06) : 1295 - 1303
  • [30] Human cytochrome P450 2A6 is the major enzyme involved in the metabolism of three alkoxyethers used as oxyfuels
    Le Gal, A
    Dréano, Y
    Gervasi, PG
    Berthou, F
    TOXICOLOGY LETTERS, 2001, 124 (1-3) : 47 - 58