Ru(ii) photosensitizers competent for hypoxic cancers via green light activation

被引：22

作者：

Ballester, Francisco J. ^{[1
,2
]}

Ortega, Enrique ^{[1
,2
]}

Bautista, Delia ^{[3
]}

Dolores Santana, M. ^{[1
,2
]}

Ruiz, Jose ^{[1
,2
]}

机构：

[1] Univ Murcia, Dept Quim Inorgan, E-30071 Murcia, Spain

[2] Biomed Res Inst Murcia IMIB Arrixaca, E-30071 Murcia, Spain

[3] Univ Murcia, SAI, E-30071 Murcia, Spain

来源：

CHEMICAL COMMUNICATIONS | 2020年 / 56卷 / 71期

关键词：

IRIDIUM(III) COMPLEXES; PHOTODYNAMIC THERAPY; LIGANDS; RUTHENIUM(II); POLYPYRIDYL; AGENTS;

D O I：

10.1039/d0cc02417a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A family of five heteroleptic complexes [Ru(C<<^>>N)(N<<^>>N)(2)][PF6] (HC<<^>>N = methyl 1-butyl-2-arylbenzimidazolecarboxylate; N<<^>>N = polypyridine) has been synthesized to act as biologically-compatible green light photosensitizers (PSs) with phototherapeutic indexes (PIs) up to higher than 700 under hypoxia (2% O-2) in HeLa cancer cells under short time of irradiation.

引用

页码：10301 / 10304

页数：4

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