ContRac1ion-Mediated Glucose Uptake: A Central Role for Rac1

被引：3
作者：
Lundell, Leonidas S. [1 ]
Krook, Anna [1 ]
机构：
[1] Karolinska Inst, Dept Physiol & Pharmacol, Sect Integrat Physiol, Stockholm, Sweden
来源：
DIABETES | 2013年 / 62卷 / 04期
关键词：
SKELETAL-MUSCLE CELLS; SURFACE GLUT4 CONTENT; EXERCISE; PROTEIN; INSULIN; PHOSPHORYLATION; TRANSLOCATION; TRANSPORTERS; CONTRACTION; BINDING;
D O I：
10.2337/db12-1789
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
引用
收藏
页码：1024 / 1025
页数：2
相关论文
共 50 条
  • [11] Rac1 and AMPK Account for the Majority of Muscle Glucose Uptake Stimulated by Ex Vivo Contraction but Not In Vivo Exercise
    Sylow, Lykke
    Moller, Lisbeth L. V.
    Kleinert, Maximilian
    D'Hulst, Gommaar
    De Groote, Estelle
    Schjerling, Peter
    Steinberg, Gregory R.
    Jensen, Thomas E.
    Richter, Erik A.
    DIABETES, 2017, 66 (06) : 1548 - 1559
  • [12] Tiam1 mediates Rac1 activation and contraction-induced glucose uptake in skeletal muscle cells
    Yue, Yingying
    Zhang, Chang
    Zhao, Xiaoyun
    Liu, Sasa
    Lv, Xiaoting
    Zhang, Shitian
    Yang, Jianming
    Chen, Liming
    Duan, Hongquan
    Zhang, Youyi
    Yao, Zhi
    Niu, Wenyan
    FASEB JOURNAL, 2021, 35 (02)
  • [13] Stretch-stimulated glucose transport in skeletal muscle is regulated by Rac1
    Sylow, Lykke
    Moller, Lisbeth L. V.
    Kleinert, Maximilian
    Richter, Erik A.
    Jensen, Thomas E.
    JOURNAL OF PHYSIOLOGY-LONDON, 2015, 593 (03): : 645 - 656
  • [14] A Crucial Role for the Small GTPase Rac1 Downstream of the Protein Kinase Akt2 in Insulin Signaling that Regulates Glucose Uptake in Mouse Adipocytes
    Takenaka, Nobuyuki
    Nakao, Mika
    Matsui, Sayaka
    Satoh, Takaya
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2019, 20 (21)
  • [15] Role for RalA downstream of Rac1 in skeletal muscle insulin signalling
    Takenaka, Nobuyuki
    Sumi, Yukio
    Matsuda, Keiko
    Fujita, Junko
    Hosooka, Tetsuya
    Noguchi, Tetsuya
    Aiba, Atsu
    Satoh, Takaya
    BIOCHEMICAL JOURNAL, 2015, 469 : 445 - 454
  • [16] An AMPK/Axin1-Rac1 signaling pathway mediates contraction-regulated glucose uptake in skeletal muscle cells
    Yue, Yingying
    Zhang, Chang
    Zhang, Xuejiao
    Zhang, Shitian
    Liu, Qian
    Hu, Fang
    Lv, Xiaoting
    Li, Hanqi
    Yang, Jianming
    Wang, Xinli
    Chen, Liming
    Yao, Zhi
    Duan, Hongquan
    Niu, Wenyan
    AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM, 2020, 318 (03): : E330 - E342
  • [17] Kalirin mediates Rac1 activation downstream of calcium/calmodulin-dependent protein kinase II to stimulate glucose uptake during muscle contraction
    Liu, Sasa
    Qi, Rui
    Zhang, Juan
    Zhang, Chang
    Chen, Liming
    Yao, Zhi
    Niu, Wenyan
    FEBS LETTERS, 2022, 596 (24) : 3159 - 3175
  • [18] Atrophy of White Adipose Tissue Accompanied with Decreased Insulin-Stimulated Glucose Uptake in Mice Lacking the Small GTPase Rac1 Specifically in Adipocytes
    Hasegawa, Kiko
    Takenaka, Nobuyuki
    Tanida, Kenya
    Chan, Man Piu
    Sakata, Mizuki
    Aiba, Atsu
    Satoh, Takaya
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2021, 22 (19)
  • [19] Akt and Rac1 signaling are jointly required for insulin-stimulated glucose uptake in skeletal muscle and downregulated in insulin resistance
    Sylow, Lykke
    Kleinert, Maximilian
    Pehmoller, Christian
    Prats, Clara
    Chiu, Tim T.
    Klip, Amira
    Richter, Erik A.
    Jensen, Thomas E.
    CELLULAR SIGNALLING, 2014, 26 (02) : 323 - 331
  • [20] The Role of Rac1 in Glycoprotein Ib-IX-Mediated Signal Transduction and Integrin Activation
    Delaney, M. Keegan
    Liu, Junling
    Zheng, Yi
    Berndt, Michael C.
    Du, Xiaoping
    ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2012, 32 (11) : 2761 - 2768
12345