COVID-19 and anosmia: A review based on up-to-date knowledge

被引:257
作者
Meng, Xiangming [1 ]
Deng, Yanzhong [2 ]
Dai, Zhiyong [1 ]
Meng, Zhisheng [3 ]
机构
[1] Wuxi Huishan Dist Peoples Hosp, Dept Otolaryngol, 2 Zhanqian North Rd, Wuxi 214187, Jiangsu, Peoples R China
[2] Wuxi Huishan Dist Peoples Hosp, Dept Anesthesiol, 2 Zhanqian North Rd, Wuxi 214187, Jiangsu, Peoples R China
[3] Kunming Univ Sci & Technol, Fac Informat Engn & Automat, 727 South Jingming Rd, Kunming 650500, Yunnan, Peoples R China
关键词
Coronavirus; SARS-CoV-2; COVID-19; Anosmia; Smell; Olfactory dysfunction; Otolaryngology;
D O I
10.1016/j.amjoto.2020.102581
中图分类号
R76 [耳鼻咽喉科学];
学科分类号
100213 ;
摘要
The pandemic of Coronavirus Disease 2019 (COVID-19) has caused a vast disaster throughout the world. There is increasing evidence that olfactory dysfunction can present in COVID-19 patients. Anosmia can occur alone or can be accompanied by other symptoms of COVID-19, such as a dry cough. However, the pathogenic mechanism of olfactory dysfunction and its clinical characteristics in patients with COVID-19 remains unclear. Multiple cross-sectional studies have demonstrated that the incidence rate of olfactory dysfunction in COVID-19 patients varies from 33.9-68% with female dominance. Anosmia and dysgeusia are often comorbid in COVID-19 patients. Otolaryngologists should be mindful of the symptom of anosmia in outpatients so as not to delay the diagnosis of COVID-19. In this paper, we have reviewed the relevant knowledge based on up-to-date literature.
引用
收藏
页数:6
相关论文
共 56 条
[1]   OLFACTORY THRESHOLD AND NASAL MUCOSAL CHANGES IN EXPERIMENTALLY-INDUCED COMMON COLD [J].
AKERLUND, A ;
BENDE, M ;
MURPHY, C .
ACTA OTO-LARYNGOLOGICA, 1995, 115 (01) :88-92
[2]  
American Academy of Otolaryngology-Head and Neck Surgery, AN NEW COVID 19 AN R
[3]  
[Anonymous], 2020, JAMA NEUROL, DOI DOI 10.1001/JAMANEUROL.2020.0387
[4]  
Bagheri Seyed Hamidreza, 2020, Med J Islam Repub Iran, V34, P62, DOI 10.34171/mjiri.34.62
[5]   Neurological manifestations in COVID-19 caused by SARS-CoV-2 [J].
Baig, Abdul Mannan .
CNS NEUROSCIENCE & THERAPEUTICS, 2020, 26 (05) :499-501
[6]   Evidence of the COVID-19 Virus Targeting the CNS: Tissue Distribution, Host-Virus Interaction, and Proposed Neurotropic Mechanisms [J].
Baig, Abdul Mannan ;
Khaleeq, Areeba ;
Ali, Usman ;
Syeda, Hira .
ACS CHEMICAL NEUROSCIENCE, 2020, 11 (07) :995-998
[7]  
Beltrán-Corbellini A, 2020, EUR J NEUROL, V27, P1738, DOI 10.1111/ene.14273
[8]   Medical nowcasting using Google trends: application in otolaryngology [J].
Braun, Thomas ;
Harreus, Ulrich .
EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY, 2013, 270 (07) :2157-2160
[9]  
Centers for Disease Control and Prevention, SYMPT COR
[10]   SARS-CoV-2 Isolation From Ocular Secretions of a Patient With COVID-19 in Italy With Prolonged Viral RNA Detection [J].
Colavita, Francesca ;
Lapa, Daniele ;
Carletti, Fabrizio ;
Lalle, Eleonora ;
Bordi, Licia ;
Marsella, Patrizia ;
Nicastri, Emanuele ;
Bevilacqua, Nazario ;
Giancola, Maria Letizia ;
Corpolongo, Angela ;
Ippolito, Giuseppe ;
Capobianchi, Maria Rosaria ;
Castilletti, Concetta .
ANNALS OF INTERNAL MEDICINE, 2020, 173 (03) :242-+