COVID-19 and anosmia: A review based on up-to-date knowledge

被引:253
作者
Meng, Xiangming [1 ]
Deng, Yanzhong [2 ]
Dai, Zhiyong [1 ]
Meng, Zhisheng [3 ]
机构
[1] Wuxi Huishan Dist Peoples Hosp, Dept Otolaryngol, 2 Zhanqian North Rd, Wuxi 214187, Jiangsu, Peoples R China
[2] Wuxi Huishan Dist Peoples Hosp, Dept Anesthesiol, 2 Zhanqian North Rd, Wuxi 214187, Jiangsu, Peoples R China
[3] Kunming Univ Sci & Technol, Fac Informat Engn & Automat, 727 South Jingming Rd, Kunming 650500, Yunnan, Peoples R China
关键词
Coronavirus; SARS-CoV-2; COVID-19; Anosmia; Smell; Olfactory dysfunction; Otolaryngology;
D O I
10.1016/j.amjoto.2020.102581
中图分类号
R76 [耳鼻咽喉科学];
学科分类号
100213 ;
摘要
The pandemic of Coronavirus Disease 2019 (COVID-19) has caused a vast disaster throughout the world. There is increasing evidence that olfactory dysfunction can present in COVID-19 patients. Anosmia can occur alone or can be accompanied by other symptoms of COVID-19, such as a dry cough. However, the pathogenic mechanism of olfactory dysfunction and its clinical characteristics in patients with COVID-19 remains unclear. Multiple cross-sectional studies have demonstrated that the incidence rate of olfactory dysfunction in COVID-19 patients varies from 33.9-68% with female dominance. Anosmia and dysgeusia are often comorbid in COVID-19 patients. Otolaryngologists should be mindful of the symptom of anosmia in outpatients so as not to delay the diagnosis of COVID-19. In this paper, we have reviewed the relevant knowledge based on up-to-date literature.
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页数:6
相关论文
共 56 条
  • [1] OLFACTORY THRESHOLD AND NASAL MUCOSAL CHANGES IN EXPERIMENTALLY-INDUCED COMMON COLD
    AKERLUND, A
    BENDE, M
    MURPHY, C
    [J]. ACTA OTO-LARYNGOLOGICA, 1995, 115 (01) : 88 - 92
  • [2] American Academy of Otolaryngology-Head and Neck Surgery, AN NEW COVID 19 AN R
  • [3] [Anonymous], 2020, JAMA NEUROL, DOI [DOI 10.1001/JAMANEUROL.2020.0387, 10.1001/jamaneurol.2020.1127]
  • [4] [Anonymous], 2020, N. Engl. J. Med., DOI DOI 10.1056/NEJMoa2001316
  • [5] Bagheri Seyed Hamidreza, 2020, Med J Islam Repub Iran, V34, P62, DOI 10.34171/mjiri.34.62
  • [6] Neurological manifestations in COVID-19 caused by SARS-CoV-2
    Baig, Abdul Mannan
    [J]. CNS NEUROSCIENCE & THERAPEUTICS, 2020, 26 (05) : 499 - 501
  • [7] Evidence of the COVID-19 Virus Targeting the CNS: Tissue Distribution, Host-Virus Interaction, and Proposed Neurotropic Mechanisms
    Baig, Abdul Mannan
    Khaleeq, Areeba
    Ali, Usman
    Syeda, Hira
    [J]. ACS CHEMICAL NEUROSCIENCE, 2020, 11 (07): : 995 - 998
  • [8] Acute-onset smell and taste disorders in the context of COVID-19: a pilot multicentre polymerase chain reaction based case-control study
    Beltran-Corbellini, A.
    Chico-Garcia, J. L.
    Martinez-Poles, J.
    Rodriguez-Jorge, F.
    Natera-Villalba, E.
    Gomez-Corral, J.
    Gomez-Lopez, A.
    Monreal, E.
    Parra-Diaz, P.
    Cortes-Cuevas, J. L.
    Galan, J. C.
    Fragola-Arnau, C.
    Porta-Etessam, J.
    Masjuan, J.
    Alonso-Canovas, A.
    [J]. EUROPEAN JOURNAL OF NEUROLOGY, 2020, 27 (09) : 1738 - 1741
  • [9] Medical nowcasting using Google trends: application in otolaryngology
    Braun, Thomas
    Harreus, Ulrich
    [J]. EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY, 2013, 270 (07) : 2157 - 2160
  • [10] Center for Disease Control and Prevention, SYMPT COR