Synergy Between Novel Antimicrobials and Conventional Antibiotics or Bacteriocins

被引:52
作者
Wolska, Krystyna I. [1 ]
Grzes, Katarzyna [1 ]
Kurek, Anna [1 ]
机构
[1] Univ Warsaw, Inst Microbiol, Dept Bacterial Genet, Fac Biol, PL-02096 Warsaw, Poland
关键词
antibiotics; bacteriophages; nanoparticles; plant compounds; synergy; RESISTANT STAPHYLOCOCCUS-AUREUS; ESCHERICHIA-COLI BIOFILM; LYTIC ENZYME CPL-1; IN-VITRO ACTIVITY; SILVER NANOPARTICLES; ANTIBACTERIAL ACTIVITY; PSEUDOMONAS-AERUGINOSA; STREPTOCOCCUS-PNEUMONIAE; EPIGALLOCATECHIN GALLATE; OLEANOLIC ACID;
D O I
10.33073/pjm-2012-012
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Due to the alarming spread of resistance to classic antimicrobial agents, innovative therapeutic methods to combat antibiotic-resistant bacterial pathogens are urgently required. This minireview examines the enhancement of antibiotic efficacy by their combination with new antimicrobials, such as plant-derived compounds, metal ions and nanoparticles and bacteriophage lytic enzymes. The mechanisms of the observed synergy are also described. The promising results of basic research indicate that in future, combined therapy may be applied in human and veterinary medicine, agriculture and the food industry to combat bacterial pathogens.
引用
收藏
页码:95 / 104
页数:10
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