Binding of Haemophilus ducreyi to extracellular matrix proteins

被引：23

作者：

Bauer, ME

Spinola, SM

机构：

[1] Indiana Univ, Sch Med, Dept Med, Indianapolis, IN 46202 USA

[2] Indiana Univ, Sch Med, Dept Microbiol & Immunol, Indianapolis, IN 46202 USA

[3] Indiana Univ, Sch Med, Dept Pathol & Lab Med, Indianapolis, IN 46202 USA

来源：

INFECTION AND IMMUNITY | 1999年 / 67卷 / 05期

关键词：

D O I：

10.1128/IAI.67.5.2649-2652.1999

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

We developed an enzyme-linked immunosorbent assay-based assay to assess Haemophilus ducryi binding to extracellular matrix (ECM) proteins. H. ducreyi 35000HP bound to fibronectin, laminin, and type I and III collagen but not to type TV, V, or VI collagen or elastin. Isogenic strains with mutations in ftpA or losB bound as well as the parent, suggesting that neither pill nor full-length lipooligosaccharide is required for H. ducreyi to bind to ECM proteins.

引用

收藏

页码：2649 / 2652

页数：4

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