IgE reactivity to a Cry j 3, an allergen of Japanese cedar (Cryptomeria japonica) pollen in dogs with canine atopic dermatitis

被引：11

作者：

Kubota, Shota ^{[1
]}

Miyaji, Kazuki ^{[1
]}

Shimo, Yusaku ^{[1
]}

Shimakura, Hidekatsu ^{[1
]}

Takase, Yukari ^{[1
]}

Okamoto, Noriaki ^{[1
]}

Kiuchi, Akio ^{[1
]}

Fujimura, Masato ^{[2
]}

Fujimura, Takashi ^{[3
]}

DeBoer, Douglas J. ^{[4
]}

Tsukui, Toshihiro ^{[5
]}

Sakaguchi, Masahiro ^{[1
]}

机构：

[1] Azabu Univ, Sch Vet Med, Dept Vet Microbiol, Chuo Ku, Sagamihara, Kanagawa 2525201, Japan

[2] Fujimura Anim Hosp, Osaka 6520022, Japan

[3] RIKEN, Res Ctr Allergy & Immunol, Tsurumi Ku, Yokohama, Kanagawa 2300045, Japan

[4] Univ Wisconsin, Sch Vet Med, Dept Med Sci, Madison, WI 53706 USA

[5] Nippon Zenyaku Kogyo Co Ltd, Koriyama, Fukushima 9630196, Japan

来源：

VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY | 2012年 / 149卷 / 1-2期

关键词：

Allergen; Canine atopic dermatitis; IgE; Japanese cedar pollen; MAJOR ALLERGEN; J-I; ANTIBODIES; EXPRESSION; TOMATO;

D O I：

10.1016/j.vetimm.2012.06.007

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The present study investigated IgE reactivity to a new Cryptomeria japonica pollen allergen (Cry j 3) in dogs with atopic dermatitis by using a fluorometric ELISA. Serum samples from 15 dogs that showed IgE sensitivity to crude C. japonica pollen allergen by ELISA were tested for specific IgE to each allergen, individually. All 15 dogs had anti-Cry j 1 lgE, 6 (40%) had anti-Cry j 2 IgE, and 11 (73%) had anti-Cry j 3 IgE. Further, we found that these anti-Cry j 3 IgE reacted to Cry j 3 with immunoblotting analysis. These findings indicate that Cry j 3 may be a major allergen in dogs. (C) 2012 Elsevier B.V. All rights reserved.

引用

页码：132 / 135

页数：4

共 22 条

[1] Cloning and expression of a major allergen from Cupressus arizonica pollen, Cup a 3, a PR-5 protein expressed under polluted environment [J].

Cortegano, I ;

Civantos, E ;

Aceituno, E ;

del Moral, A ;

López, E ;

Lombardero, M ;

del Pozo, V ;

Lahoz, C .

ALLERGY, 2004, 59 (05) :485-490

[2] PRODUCTION AND CHARACTERIZATION OF MOUSE MONOCLONAL-ANTIBODIES DIRECTED AGAINST CANINE IGE AND IGG [J].

DEBOER, DJ ;

EWING, KM ;

SCHULTZ, KT .

VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 1993, 37 (3-4) :183-199

[3] Oral allergy syndrome induced by tomato in a dog with Japanese cedar (Cryptomeria japonica) pollinosis [J].

Fujimura, M ;

Ohmori, K ;

Masuda, K ;

Tsujimoto, H ;

Sakaguchi, M .

JOURNAL OF VETERINARY MEDICAL SCIENCE, 2002, 64 (11) :1069-1070

[4] Isolation and characterization of native Cry j 3 from Japanese cedar (Cryptomeria japonica) pollen [J].

Fujimura, T. ;

Futamura, N. ;

Midoro-Horiuti, T. ;

Togawa, A. ;

Goldblum, R. M. ;

Yasueda, H. ;

Saito, A. ;

Shinohara, K. ;

Masuda, K. ;

Kurata, K. ;

Sakaguchi, M. .

ALLERGY, 2007, 62 (05) :547-553

[5] Revised nomenclature for veterinary allergy [J].

Halliwell, Richard .

VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 2006, 114 (3-4) :207-208

[6] SENSITIVITY TO 2 MAJOR ALLERGENS (CRY-J-I AND CRY-J-II) IN PATIENTS WITH JAPANESE CEDAR (CRYPTOMERIA-JAPONICA) POLLINOSIS [J].

HASHIMOTO, M ;

NIGI, H ;

SAKAGUCHI, M ;

INOUYE, S ;

IMAOKA, K ;

MIYAZAWA, H ;

TANIGUCHI, Y ;

KURIMOTO, M ;

YASUEDA, H ;

OGAWA, T .

CLINICAL AND EXPERIMENTAL ALLERGY, 1995, 25 (09) :848-852

[7] PREVALENCE OF IGE ANTIBODY TO CRUDE AND PURIFIED ALLERGENS OF JAPANESE CEDAR POLLEN AMONG DIFFERENT TROOPS OF JAPANESE MONKEYS (MACACA-FUSCATA) [J].

HASHIMOTO, M ;

SAKAGUCHI, M ;

INOUYE, S ;

IMAOKA, K ;

NIGI, H ;

FUJIMOTO, K ;

HONJO, S ;

TANIGUCHI, Y ;

KURIMOTO, M ;

GOTOH, S ;

MINEZAWA, M ;

YOKATA, A .

JOURNAL OF MEDICAL PRIMATOLOGY, 1994, 23 (07) :393-396

[8] Assessment of cross-reactivity between Japanese cedar (Cryptomeria japonica) pollen and tomato fruit extracts by RAST inhibition and immunoblot inhibition [J].

Kondo, Y ;

Tokuda, R ;

Urisu, A ;

Matsuda, T .

CLINICAL AND EXPERIMENTAL ALLERGY, 2002, 32 (04) :590-594

[9]

Kondo Yasuto, 2009, Allergology International, V58, P485, DOI 10.2332/allergolint.09-RAI-0136

[10] IgE-reactivity to major Japanese cedar (Cryptomeria japonica) pollen allergens (Cry j 1 and Cry j 2) by ELISA in dogs with atopic dermatitis [J].

Masuda, K ;

Tsujimoto, H ;

Fujiwara, S ;

Kurata, K ;

Hasegawa, A ;

Taniguchi, Y ;

Yamashita, K ;

Yasueda, H ;

DeBoer, DJ ;

de Weck, AL ;

Sakaguchi, M .

VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 2000, 74 (3-4) :263-270

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