Notoamides F-K, Prenylated Indole Alkaloids Isolated from a Marine-Derived Aspergillus sp.

被引：126

作者：

Tsukamoto, Sachiko ^{[1
,2
]}

Kato, Hikaru ^{[2
]}

Samizo, Masayuki ^{[2
]}

Nojiri, Yuka ^{[2
]}

Onuki, Hiroyuki ^{[3
]}

Hirota, Hiroshi ^{[3
]}

Ohta, Tomihisa ^{[2
]}

机构：

[1] Chiba Univ, Grad Sch Sci, Inage Ku, Chiba 2638522, Japan

[2] Kanazawa Univ, Grad Sch Nat Sci & Technol, Kanazawa, Ishikawa 9201192, Japan

[3] RIKEN GSC, Tsurumi Ku, Yokohama, Kanagawa 2300045, Japan

来源：

JOURNAL OF NATURAL PRODUCTS | 2008年 / 71卷 / 12期

关键词：

D O I：

10.1021/np800471y

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Six new prenylated indole alkaloids, named notoamides F-K (8-13), were isolated from a marine-derived Aspergillus sp. Their structures, including absolute configurations, were elucidated by spectroscopic methods. Notoamide I (11) showed weak cytotoxicity against HeLa cells with an IC(50) value of 21 mu g/mL.

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页码：2064 / 2067

页数：4

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