Selected Synthetic Strategies to Spirocyclics

被引：287

作者：

Kotha, Sambasivarao ^{[1
]}

Deb, Ashoke Chandra ^{[1
]}

Lahiri, Kakali ^{[1
]}

Manivannan, Ethirajan ^{[1
]}

机构：

[1] Indian Inst Technol, Dept Chem, Bombay 400076, Maharashtra, India

来源：

SYNTHESIS-STUTTGART | 2009年 / 02期

关键词：

spiro compounds; metathesis; Diels-Alder reactions; domino reactions; Suzuki coupling; radical reactions; ring closure; RING-CLOSING METATHESIS; CARBOCYCLIC SPIRO COMPOUNDS; ASYMMETRIC TOTAL-SYNTHESIS; FORMAL TOTAL-SYNTHESIS; CLAISEN REARRANGEMENT; STEREOSELECTIVE CONSTRUCTION; STEREOCONTROLLED SYNTHESIS; ENANTIOSELECTIVE SYNTHESIS; ENANTIOMERICALLY PURE; CYCLIZATION APPROACH;

D O I：

10.1055/s-0028-1083300

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The design and synthesis of spirocycles is a challenging task because it involves the creation of a quaternary center, which itself is considered to be one of the most difficult tasks among synthetic transformations. Some recent approaches based on metathesis, cycloaddition and transition-metal-mediated transformations to spirocycles are described here.

引用

页码：165 / +

页数：27

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