A highly efficient one-pot method for the synthesis of thioureas and 2-imino-4-thiazolidinones under microwave conditions

被引：24

作者：

Chau, Chi-Min ^{[1
,2
]}

Chuan, Tzu-Jung ^{[1
]}

Liu, Kuan-Miao ^{[1
,2
]}

机构：

[1] Chung Shan Med Univ, Sch Appl Chem, Taichung 40201, Taiwan

[2] Chung Shan Med Univ Hosp, Dept Med Educ, Taichung 40201, Taiwan

来源：

RSC ADVANCES | 2014年 / 4卷 / 03期

关键词：

ORGANIC-SYNTHESIS; ASYMMETRIC CATALYSIS; CARBONYL-COMPOUNDS; DERIVATIVES; ORGANOCATALYSIS; CHEMISTRY; RECEPTOR; AMINES;

D O I：

10.1039/c3ra46270f

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A one-pot synthesis of symmetrical and unsymmetrical substituted thioureas and 2-imino-4-thiazolidinones from simple starting materials under microwave irradiation and solventless conditions without base additives is presented. Various di- and trisubstituted thioureas are obtained in good yields in a few minutes. The sequential, three-component, one-pot synthesis of 2-imino-4-thiazolidinone derivatives is also studied, with satisfactory results obtained.

引用

页码：1276 / 1282

页数：7

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