Multidisciplinary Management of Gastric Cancer

被引：12

作者：

Misleh, Jamal G. ^{[1
]}

Santoro, Peter ^{[2
]}

Strasser, Jonathon F.

Bennett, Joseph J. ^{[2
]}

机构：

[1] Christiana Care Hosp, Helen F Graham Canc Ctr, Med Oncol Hematol Consultants, Dept Med Oncol, Newark, DE 19713 USA

[2] Christiana Care Hosp, Helen F Graham Canc Ctr, Dept Surg, 4701 Ogletown Stanton Rd,Suite 4000, Newark, DE 19713 USA

来源：

SURGICAL ONCOLOGY CLINICS OF NORTH AMERICA | 2013年 / 22卷 / 02期

关键词：

Gastric cancer; D2; lymphadenectomy; Multidisciplinary; Adjuvant; Chemotherapy; LYMPH-NODE DISSECTION; PHASE-III TRIAL; MARUYAMA INDEX SURGERY; ADJUVANT CHEMOTHERAPY; RANDOMIZED-TRIAL; GASTROESOPHAGEAL ADENOCARCINOMA; CURATIVE RESECTION; PLUS CISPLATIN; PERIOPERATIVE CHEMOTHERAPY; 1ST-LINE TREATMENT;

D O I：

10.1016/j.soc.2012.12.013

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Multidisciplinary Management of Gastric Cancer Jamal G. Misleh, Peter Santoro, Jonathon F. Strasser, and Joseph J. Bennett Treatment of gastric cancer involves a multidisciplinary approach to achieve long-term outcome, including surgery, chemotherapy, and radiation therapy. Most patients present with advanced disease and are not candidates for a curative approach. Palliative chemotherapy is recommended for symptom control and for short-term advances in survival. Surgery combined with different chemotherapy and chemoradiation options improves survival. Initial studies focused on adjuvant chemoradiation and showed improved survival. More recent trials have demonstrated that perioperative chemotherapy before and after surgery provides a survival advantage. Such an approach may also downstage marginal patients who can then be selected to undergo curative resection and complete adjuvant chemotherapy.

引用

页码：247 / 264

页数：18