Alfa-fetoprotein secreting ovarian sex cord-stromal tumor

被引：6

作者：

Jashnani, Kusum D. ^{[1
]}

Hegde, Chandrashekar V. ^{[2
]}

Munot, Shrutika P. ^{[1
]}

机构：

[1] TN Med Coll & BYL Nair Ch Hosp, Dept Pathol, Bombay, Maharashtra, India

[2] TN Med Coll & BYL Nair Ch Hosp, Dept Obstetr & Gynecol, Bombay, Maharashtra, India

来源：

INDIAN JOURNAL OF PATHOLOGY AND MICROBIOLOGY | 2013年 / 56卷 / 01期

关键词：

Elevated serum alpha-fetoprotein; ovarian tumor; sex cord-stromal tumor; LEYDIG CELL TUMOR;

D O I：

10.4103/0377-4929.116152

中图分类号：

R36 [病理学];

学科分类号：

100104 ;

摘要：

Ovarian sex cord-stromal tumors are relatively infrequent neoplasms that account for approximately 8% of all primary ovarian tumors. They are a heterogeneous group of neoplasms composed of cells derived from gonadal sex cords (granulosa and Sertoli cells), specialized gonadal stroma (theca and Leydig cells), and fibroblasts. They may show androgenic or estrogenic manifestations. We report such a tumor associated with markedly raised serum alpha-fetoprotein (AFP) levels in a young female presenting with a mass and defeminising symptoms. Serum AFP levels returned to normal on removal of tumor.

引用

页码：54 / 56

页数：3

共 9 条

[1] RAISED SERUM ALPHA-FETOPROTEIN IN SERTOLI-LEYDIG CELL TUMOR (ANDROBLASTOMA) OF OVARY - REPORT OF 2 CASES [J].

CHADHA, S ;

HONNEBIER, WJ ;

SCHABERG, A .

INTERNATIONAL JOURNAL OF GYNECOLOGICAL PATHOLOGY, 1987, 6 (01) :82-88

[2]

GAGNON S, 1989, MODERN PATHOL, V2, P63

[3]

Jang Kee-Taek, 2002, Journal of Pathology and Translational Medicine, V36, P128

[4] Hepatocytic differentiation in retiform Sertoli-Leydig cell tumors: Distinguishing a heterologous element from Leydig cells [J].

Mooney, EE ;

Nogales, FF ;

Tavassoli, FA .

HUMAN PATHOLOGY, 1999, 30 (06) :611-617

[5] Sertoli cell tumors of the ovary - A clinicopothologic ond immunohistochemicol study of 54 cases [J].

Oliva, E ;

Alvarez, TE ;

Young, RH .

AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 2005, 29 (02) :143-156

[6]

Poli U. R., 2009, Indian Journal of Cancer, V46, P64, DOI 10.4103/0019-509X.48599

[7] Juvenile granulosa cell tumour with hepatocyte-like cells and raised serum alpha-fetoprotein [J].

Smith, Richard ;

Moss, Jill ;

Shore, Ian ;

El-Bahrawy, Mona A. .

HISTOPATHOLOGY, 2010, 57 (04) :637-641

[8]

TETU B, 1986, ARCH PATHOL LAB MED, V110, P65

[9]

Wenham RM, 2002, J GYNECOL ONCOL, V7, P121

← 1 →