Prevalence of parvovirus B 19 infection in children with aplastic anemia

被引：8

作者：

Gupta, Vineeta ^{[1
]}

Saini, Isha ^{[1
]}

Nath, Gopal ^{[2
]}

机构：

[1] Banaras Hindu Univ, Inst Med Sci, Dept Pediat, Varanasi 221005, Uttar Pradesh, India

[2] Banaras Hindu Univ, Inst Med Sci, Dept Microbiol, Varanasi 221005, Uttar Pradesh, India

来源：

INDIAN PEDIATRICS | 2013年 / 50卷 / 05期

关键词：

Aplastic anemia; Etiology; Children; Parvovirus B19; B19;

D O I：

10.1007/s13312-013-0149-2

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

We studied the prevalence of parvovirus B19 infection in pediatric patients with acquired aplastic anemia. Detection of parvovirus B19 DNA by PCR and IgM antibodies by ELISA was carried out in 66 pediatric patients with acquired aplastic anemia. 45 healthy children acted as controls. Parvovirus B19 DNA was detected in significantly higher number of patients in comparison to controls (27% vs 2%, P = 0.001). Similarly, parvovirus B19 IgM antibodies were detected in 17 (25.8%) patients as against one control (2.2%) (P < 0.05). Clinical and hematological profile of the patients with or without parvovirus infection was comparable.

引用

页码：489 / 491

页数：3

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