A high temperature heat pipe heat exchanger consists of heat pipes filled with different working media inside. In different temperature zones, heat pipes with different working media are linked safely by controlling the vapor temperature, the media inside the heat pipe. The vapor temperature inside the pipe is heavily affected by the temperature field of fluid outside the heat pipes and the heat transfer performance inside the heat pipe, while the heat transfer performance inside the pipe in turn has a bearing on the temperature distribution of fluid outside the pipe. to coordinate the fluid temperature distribution both inside and outside the pipes, study on local heat transfer enhancement has been conducted on high temperature heat pipe heat exchanger in this article, and CFD computational software was used to make rational and accurate prediction of fluid temperature distribution both inside and outside the pipes, so as to provide economic and reliable design basis for high temperature heat pipe heat exchanger.