Rapid preparation of novel MgNH4PO4•H2O porous scaffolds via 3D-printing combined with a hydrothermal-process-assisted post treatment

被引：2

作者：

Cao, Xiaofeng ^{[1
]}

Zhang, Linlin ^{[1
]}

Chen, Qifeng ^{[2
]}

Zhang, Bing ^{[1
]}

Guo, Lin ^{[1
]}

Guo, Yanchuan ^{[1
,3
]}

机构：

[1] Chinese Acad Sci, Tech Inst Phys & Chem, Key Lab Photochem Convers & Optoelect Mat, Beijing 100190, Peoples R China

[2] Univ Jinan, Sch Mat Sci & Engn, Jinan 250022, Shandong, Peoples R China

[3] Univ Chinese Acad Sci, Beijing 100049, Peoples R China

来源：

CERAMICS INTERNATIONAL | 2020年 / 46卷 / 12期

基金：

中国国家自然科学基金;

关键词：

Extrusion; MgO; Biomedical applications; Hydrothermal process; BIO-NANOCOMPOSITE SCAFFOLDS; BEAM-TYPE IMPLANTS; COMPOSITE SCAFFOLDS; TISSUE APPLICATIONS; IN-VITRO; BONE; FABRICATION; STRUVITE; REGENERATION; DECOMPOSITION;

D O I：

10.1016/j.ceramint.2020.05.013

中图分类号：

TQ174 [陶瓷工业]; TB3 [工程材料学];

学科分类号：

0805 ; 080502 ;

摘要：

Novel dittmarite (MgNH4PO4 center dot H2O) 3D porous scaffolds were firstly fabricated via 3D-printing combined with a hydrothermal-process-assisted post treatment. Powder X-ray diffraction (XRD), scanning electron microscopy (SEM), and energy dispersive spectroscopy (EDS) were used to characterize the phases, morphologies, and element compositions of the 3D porous structures. The hydrothermal process played the key role in the formation of dittmarite phase. The porosity, compressive strength, and in vitro degradation of the dittmarite scaffolds were studied in detail. In addition, the cytotoxicity on MC3T3-E1 osteoblast cells and cell adhesion were evaluated and the results showed that the dittmarite porous scaffold possessed superior cytocompatibility and could support MC3T3-E1 cellular attachment. The research indicated that dittmarite porous scaffolds had a wide application prospect in bone tissue repair fields.

引用

页码：19792 / 19798

页数：7

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