Fast break on the fat brake:: Mechanism of peroxisome proliferator-activated receptor-δ regulation of lipid accumulation in hepatocytes

被引:4
作者
Andrews, Danielle B.
Schwimmer, Jeffrey B.
Lavine, Joel E.
机构
[1] Univ Calif San Diego, Div Gastroenterol Hepatol & Nutr, San Diego, CA 92103 USA
[2] Rady Childrens Hosp San Diego, San Diego, CA USA
关键词
D O I
10.1002/hep.22505
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
引用
收藏
页码:355 / 357
页数:3
相关论文
共 13 条
  • [1] Nonalcoholic fatty liver disease as a complication of insulin resistance
    Abdelmalek, Manal F.
    Diehl, Anna Mae
    [J]. MEDICAL CLINICS OF NORTH AMERICA, 2007, 91 (06) : 1125 - +
  • [2] PPARδ:: a dagger in the heart of the metabolic syndrome
    Barish, GD
    Narkar, VA
    Evans, RM
    [J]. JOURNAL OF CLINICAL INVESTIGATION, 2006, 116 (03) : 590 - 597
  • [3] Anatomical profiling of nuclear receptor expression reveals a hierarchical transcriptional network
    Bookout, Angie L.
    Jeong, Yangsik
    Downes, Michael
    Yu, Ruth T.
    Evans, Ronald M.
    Mangelsdorf, David J.
    [J]. CELL, 2006, 126 (04) : 789 - 799
  • [4] The oxidative stress mediator 4-hydroxynonenal is an intracellular agonist of the nuclear receptor peroxisome proliferator-activated receptor-β/δ (PPARβ/δ)
    Coleman, Jeffrey D.
    Prabhu, K. Sandeep
    Thompson, Jerry T.
    Reddy, P. Sreenivasula
    Peters, Jeffrey M.
    Peterson, Blake R.
    Reddy, C. Channa
    Vanden Heuvel, John P.
    [J]. FREE RADICAL BIOLOGY AND MEDICINE, 2007, 42 (08) : 1155 - 1164
  • [5] Nonalcoholic fatty liver disease: Pathogenesis and potential for nuclear receptors as therapeutic targets
    George, Jacob
    Liddle, Christopher
    [J]. MOLECULAR PHARMACEUTICS, 2008, 5 (01) : 49 - 59
  • [6] Lavine Joel E, 2004, Clin Liver Dis, V8, P549, DOI 10.1016/j.cld.2004.04.010
  • [7] Roles of peroxisome proliferator-activated receptor delta (PPARδ) in the control of fatty acid catabolism.: A new target for the treatment of metabolic syndrome
    Luquet, S
    Lopez-Soriano, J
    Holst, D
    Gaudel, C
    Jehl-Pietri, C
    Fredenrich, A
    Grimaldi, PA
    [J]. BIOCHIMIE, 2004, 86 (11) : 833 - 837
  • [8] Effects of bezafibrate, PPAR pan-agonist, and GW501516, PPARδ agonist, on development of steatohepatitis in mice fed a methionine- and choline-deficient diet
    Nagasawa, T
    Inada, Y
    Nakano, S
    Tamura, T
    Takahashi, T
    Maruyama, K
    Yamazaki, Y
    Kuroda, J
    Shibata, N
    [J]. EUROPEAN JOURNAL OF PHARMACOLOGY, 2006, 536 (1-2) : 182 - 191
  • [9] A pilot study of ploglitazone treatment for nonalcoholic steatohepatitis
    Promrat, K
    Lutchman, G
    Uwaifo, GI
    Freedman, RJ
    Soza, A
    Heller, T
    Doo, E
    Ghany, M
    Premkumar, A
    Park, Y
    Liang, TJ
    Yanovski, JA
    Kleiner, DE
    Hoofnagle, JH
    [J]. HEPATOLOGY, 2004, 39 (01) : 188 - 196
  • [10] QIN X, 2008, HEPATOLOGY