Trifluoroacetamido substituted sialyl donors for the preparation of sialyl galactosides

被引：23

作者：

De Meo, C ^{[1
]}

Demchenko, AV ^{[1
]}

Boons, GJ ^{[1
]}

机构：

[1] Univ Georgia, Complex Carbohydrate Res Ctr, Athens, GA 30602 USA

来源：

AUSTRALIAN JOURNAL OF CHEMISTRY | 2002年 / 55卷 / 1-2期

关键词：

D O I：

10.1071/CH02018

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Glycosidations of sialyl donor (1a), bearing a trifluoroacetamido group at C5, with partially protected D-galactosyl derivatives afforded (2, 3)-linked disaccharides in high yields and excellent stereoselectivities, even when sterically hindered alcohols were used as glycosyl acceptors. Good yields but modest stereoselectivities were obtained when (1a) was glycosidated with the C6 hydroxyl of D-galactosides.

引用

页码：131 / 134

页数：4

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