SALSO-SULPHIDE THERMAL WATER IN THE PREVENTION OF RECURRENT RESPIRATORY INFECTIONS IN CHILDREN

被引：19

作者：

Varricchio, A. ^{[1
]}

Giuliano, M. ^{[1
]}

Capasso, M. ^{[1
]}

Del Gaizo, D. ^{[1
]}

Ascione, E. ^{[1
]}

De Lucia, A. ^{[1
]}

Avvisati, F. ^{[1
]}

Capuano, F. ^{[1
]}

De Rosa, G. ^{[1
]}

Di Mauro, F. ^{[1
]}

Ciprandi, G. ^{[1
]}

机构：

[1] AIVAS, Study Grp Thermal Water, Naples, Italy

来源：

INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY | 2013年 / 26卷 / 04期

关键词：

salso-sulphide thermal water; children; recurrent respiratory infections; BIOFILMS;

D O I：

10.1177/039463201302600412

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Recurrent respiratory infections (RRI) represent a social problem for both the pharmaco-economic. impact and the burden on the family. Thermal water is popularly well accepted. However, there is no scientific evidence of its preventive activity on recurrent respiratory tract infections (RRI). Therefore, the purpose of this study was to evaluate the effects of Agnano thermal water nasal irrigation on RRI prevention in children. A total of 107 children (70 males, mean age 4.5 +/- 1.2 years) with RRI were enrolled in the study. At baseline, children were randomly assigned to the treatment with: A) inhaled crenotherapy with salso-sulphide water or B) isotonic saline (NaCl 0.9%). Inhaled therapy was performed using nasal washing by Rino-jet (ASEMA srl, Milan, Italy) b.i.d. for 12 days. Nasal washing lasted 2 minutes per nostril. Immediately before washing, children inhaled 1 1 of water by stream inhalation per 2 minutes. Crenotherapy was capable of significantly reducing: the number of respiratory infections, nasal symptoms, neutrophil and bacteria count, turbinate and adenoidal hypertrophy, presence of biofilm, and blockage of ostiomeatal complex (OCM). In conclusion, this study provides the first evidence that Agnano crenotherapy may be capable of preventing RRI in children as it exerts some positive effects, such as reduction of nasal obstruction, OCM blockage, biofilm, and inflammatory events.

引用

页码：941 / 952

页数：12

共 13 条

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