Synthesis and antifungal activities of some aryl [3-(imidazol-1-yl/triazol-1-ylmethyl) benzofuran-2-yl] ketoximes

被引：77

作者：

Gundogdu-Karaburun, Nalan ^{[1
]}

Benkli, Kadriye

Tunali, Yagmur

Ucucu, Umit

Demirayak, Seref

机构：

[1] Anadolu Univ, Fac Pharm, Dept Pharmaceut Chem, TR-26470 Eskisehir, Turkey

[2] Anadolu Univ, Fac Pharm, Dept Microbiol, TR-26470 Eskisehir, Turkey

来源：

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY | 2006年 / 41卷 / 05期

关键词：

aryl [3-(imidazol-1-yl/triazol-1-ylmethyl)benzofuran-2-yl] ketoximes; antifungal activity;

D O I：

10.1016/j.ejmech.2005.12.013

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

In this study, some aryl [3-(imidazol-1-yl/triazol-1-ylmethyl)benzofuran-2-yl] ketones, aryl (3-methyl-benzofuran-2-yl) ketoximes and aryl [3(imidazol-1-yl/triazol-1-ylmethyl)benzofuran-2-yl] ketoximes were synthesised starting from 2-aryloyl-3-methyl-benzofuranes. The structure elucidation of the compounds was performed by IR, H-1-NMR, MASS spectroscopy and elemental analyses. Antifungal activities of the compounds were examined and moderate activity was obtained. (c) 2006 Elsevier SAS. All rights reserved.

引用

页码：651 / 656

页数：6

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