Spindle Orientation: Timing Is Everything

被引:1
作者
Wynshaw-Boris, Anthony [1 ]
机构
[1] Case Western Reserve Univ, Sch Med, Dept Genet & Genome Sci, Cleveland, OH 44106 USA
关键词
NEURAL STEM-CELLS; DIVISION;
D O I
10.1016/j.neuron.2013.07.005
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
In this issue of Neuron, Xie et al. (2013) identified protein phosphatase 4c (PP4c) as a new component in the regulation of spindle orientation during mammalian neurogenesis. Importantly, their findings uncovered a novel and critical temporal aspect of the regulation of spindle orientation during neurogenesis.
引用
收藏
页码:211 / 213
页数:3
相关论文
共 12 条
  • [1] Mechanisms of asymmetric stem cell division
    Knoblich, Juergen A.
    [J]. CELL, 2008, 132 (04) : 583 - 597
  • [2] The Glial Nature of Embryonic and Adult Neural Stem Cells
    Kriegstein, Arnold
    Alvarez-Buylla, Arturo
    [J]. ANNUAL REVIEW OF NEUROSCIENCE, 2009, 32 : 149 - 184
  • [3] Manzini M.C, 2011, CELL
  • [4] What disorders of cortical development tell us about the cortex: one plus one does not always make two
    Manzini, M. Chiara
    Walsh, Christopher A.
    [J]. CURRENT OPINION IN GENETICS & DEVELOPMENT, 2011, 21 (03) : 333 - 339
  • [5] Genome-Wide Analysis of Self-Renewal in Drosophila Neural Stem Cells by Transgenic RNAi
    Neumueller, Ralph A.
    Richter, Constance
    Fischer, Anja
    Novatchkova, Maria
    Neumueller, Klaus G.
    Knoblich, Juergen A.
    [J]. CELL STEM CELL, 2011, 8 (05) : 580 - 593
  • [6] Mouse Inscuteable Induces Apical-Basal Spindle Orientation to Facilitate Intermediate Progenitor Generation in the Developing Neocortex
    Postiglione, Maria Pia
    Jueschke, Christoph
    Xie, Yunli
    Haas, Gerald A.
    Charalambous, Christoforos
    Knoblich, Juergen A.
    [J]. NEURON, 2011, 72 (02) : 269 - 284
  • [7] Spindle orientation during asymmetric cell division
    Siller, Karsten H.
    Doe, Chris Q.
    [J]. NATURE CELL BIOLOGY, 2009, 11 (04) : 365 - 374
  • [8] Protein Phosphatase 4 mediates localization of the Miranda complex during Drosophila neuroblast asymmetric divisions
    Sousa-Nunes, Rita
    Chia, William
    Somers, W. Greg
    [J]. GENES & DEVELOPMENT, 2009, 23 (03) : 359 - 372
  • [9] Protein phosphatase 4 catalytic subunit regulates Cdk1 activity and microtubule organization via NDEL1 dephosphorylation
    Toyo-oka, Kazuhito
    Mori, Daisuke
    Yano, Yoshihisa
    Shiota, Masayuki
    Iwao, Hiroshi
    Goto, Hidemasa
    Inagaki, Masaki
    Hiraiwa, Noriko
    Muramatsu, Masami
    Wynshaw-Boris, Anthony
    Yoshiki, Atsushi
    Hirotsune, Shinji
    [J]. JOURNAL OF CELL BIOLOGY, 2008, 180 (06) : 1133 - 1147
  • [10] Lissencephaly: Mechanistic insights from animal models and potential therapeutic strategies
    Wynshaw-Boris, Anthony
    Pramparo, Tiziano
    Youn, Yong Ha
    Hirotsune, Shinji
    [J]. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY, 2010, 21 (08) : 823 - 830