One-pot synthesis of functionalized p-terphenyl derivatives

被引：21

作者：

Chang, Meng-Yang ^{[1
]}

Chan, Chieh-Kai ^{[1
]}

Wu, Ming-Hao ^{[1
]}

机构：

[1] Kaohsiung Med Univ, Dept Med & Appl Chem, Kaohsiung 807, Taiwan

来源：

TETRAHEDRON | 2013年 / 69卷 / 37期

关键词：

Sulfonyl p-terphenyl; Cinnamaldehydes; Allylsulfones; Aldol condensation; Electrocyclization; CROSS-COUPLING REACTIONS; INHIBITORS; ARYLATION; OLIGOMERS; VERSATILE; BIPHENYL; DESIGN; ROUTE; COX-2; RING;

D O I：

10.1016/j.tet.2013.07.023

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A one-pot synthetic route for preparing functionalized p-terphenyl derivatives 1 and 4 is developed. The route is easily carried from the treatment of cinnamyl aldehydes 2 with substituted allylsulfones 3 in good yields via the tandem intermolecular aldol condensation/intramolecular electrocyclization/oxidative dehydrogenation. (C) 2013 Elsevier Ltd. All rights reserved.

引用

页码：7916 / 7924

页数：9

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